MLN-2238
MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18945487
| Cas No. |
1072833-77-2 |
|---|---|
| Purity |
≥99% |
| Formula |
C14H19BCl2N2O4 |
| Formula Wt. |
361.03 |
| IUPAC Name |
[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid |
| Synonym |
Ixazomib |
| Appearance |
White Powder |
Tian Z, Zhao JJ, Tai YT, et al. Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells. Blood. 2012 Nov 8;120(19):3958-67. PMID: 22983447.
