Anti-MUC16 Reference Antibody (Sofituzumab vedotin) | Ubiquitin Ligase-ubiquitin-ligase.com

Product Name :
Anti-MUC16 Reference Antibody (Sofituzumab vedotin)

synonym :

productDescription :
Sofituzumab vedotin is an antibody-drug conjugate that targets MUC16, The conjugate consists of a human anti-MUC16 antibody linked to the cytotoxic agent MMAE, which is released after internalization by the cancer cell. Clinical trials have shown promising results in the treatment of ovarian and pancreatic cancer.

molecularWeight :
155 kDa

endotoxin :
<0.001 EU/ug

purity :
>95% as determined by SDS-PAGE.

formulation :
100 mM Pro-Ac 20mM Arg pH 5.0

storage :
-80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles.

reactivity :
Human, Cynomolgus [US20080311134\t]

concentration :
6.86 mg/mL

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Ubiquitin Ligase- ubiquitin-ligase

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