9-Hydroxyellipticine Hydrochloride

Description:
9-Hydroxyellipticine Hydrochloride is a synthetic analog of the natural compound ellipticine. It inhibits the transcriptional regulation of growth factors and receptors, which may be related to its anticancer activity. 9-Hydroxyellipticine Hydrochloride has been shown to inhibit cellular growth by binding to single-stranded DNA, causing cell death. This drug also inhibits platelet-derived growth factor (PDGF) receptor phosphorylation, which causes acute lung inflammation in mice. 9-Hydroxyellipticine Hydrochloride has been shown to bind to the factor X receptor (FXR), inhibiting protein synthesis and cell growth in cultured cells. The diagnostic applications of this drug are currently being explored.

Uniprot :
P31996

Description:
MG 624 is a synthetic agonist of the α7 nicotinic acetylcholine receptor (α7nAChR). It has been shown to inhibit angiogenesis, which is the growth of new blood vessels from pre-existing ones. MG 624 binds to the α7nAChR and blocks its signaling pathways, which leads to an increase in acetylcholine levels. This drug has also been shown to have anti-angiogenic effects in animal models. MG 624 is not very effective against bladder cancer cells but does inhibit the growth of other types of cancer cells such as prostate, breast and colon cancer cells. MG 624 may be used for the treatment of various cancers or for diabetic retinopathy.

Uniprot :
Q9ULZ3

Description:
Taurodeoxycholic acid (TDCA) is a bile acid that is synthesized from cholesterol in the liver. TDCA is conjugated with glycine to form taurodeoxycholate, which is then secreted into the bile and aids in digestion. TDCA has been shown to induce apoptosis by activating the death receptor pathway and inhibiting protein synthesis. It also inhibits inflammation by suppressing the production of pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α), interleukin-1 beta (IL-1β), and IL-6. Taurodeoxycholic acid has been shown to be useful in treating injury due to its ability to reduce dextran sulfate binding to tissue proteins, preventing tissue injury and cell death.

Uniprot :
O95274

Description:
Triethylene glycol is a polyether that is used as a solvent and an additive in various products. Triethylene glycol can be found in water-based paints, cosmetics, and polyurethane plastics. It has a low toxicity to humans and animals. The rate constant of the reaction between triethylene glycol and coumarin derivatives has been determined by fluorescence probe techniques. The polymerization mechanism of triethylene glycol has been studied with the aid of polyvinyl alcohol (PVA) as a model system. This polymerization mechanism depends on the coordination geometry of the reactants. The polymerization of triethylene glycol is initiated by oxidative addition to produce the monoethyl ether followed by elimination to form the corresponding diols, which are then oxidized to give the final product. Triethylene glycol is also used in cell nuclei staining techniques to identify nuclear morphology or DNA content.

Uniprot :
O15527

Description:
Starch is an energy storing polysaccharide produced by higher plants and some algae. Pure starch is a white, tasteless and odorless powder that is insoluble in cold water or alcohol. It consists of two types of polysaccharide: the linear and helical amylose (α-1,4-linked glucose) and the branched amylopectin (α-1,4 and α-1,6-linked glucose). Depending on the plant, starch generally contains 20 to 25% amylose and 75 to 80% amylopectin by weight.

Uniprot :
Q9UHF0