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Product Name :
Anti-CEACAM5 / CEA / CD66e Reference Antibody (Tusamitamab ravtansine)

synonym :

productDescription :
Tusamitamab ravtansine is a novel antibody-drug conjugate that selectively targets CEACAM5, a cell surface glycoprotein highly expressed in several tumor types. Tusamitamab ravtansine showed promising antitumor activity in patients (pts) with heavily pretreated NSQ NSCLC and high CEACAM5 expression.

molecularWeight :
144.52 kDa

endotoxin :
<0.001 EU/ug

purity :
>95% as determined by SEC-HPLC.

formulation :
100 mM Pro-Ac 20mM Arg pH 5.0

storage :
-80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.

reactivity :
Human, Cynomolgus [US9617345]

concentration :
5.75 mg/mL

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Ubiquitin Ligase- ubiquitin-ligase