On. 2016;38:9. von Meyenn F, Iurlaro M, Habibi E, Liu NQ, Salehzadeh-Yazdi A, Santos F, Petrini E, Milagre I, Yu M, Xie Z, et al. Impairment of DNA methylation maintenance will be the most important cause of global demethylation in naive embryonic stem cells. Mol Cell. 2016;62(six):848sirtuininhibitor1. Myrianthopoulos V, Cartron PF, Liutkeviciute Z, Klimasauskas S, Matulis D, Bronner C, Martinet N, Mikros E. Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation. Eur J Med Chem. 2016;114:390sirtuininhibitor. Hopfner R, Mousli M, Garnier JM, Redon R, du Manoir S, Chatton B, Ghyselinck N, Oudet P, Bronner C. Genomic structure and chromosomal mapping with the gene coding for ICBP90, a protein involved inside the regulation from the topoisomerase IIalpha gene expression. Gene. 2001;266(1sirtuininhibitor):15sirtuininhibitor3. Qu X, Davison J, Du L, Storer B, Stirewalt DL, Heimfeld S, Estey E, Appelbaum FR, Fang M. Identification of differentially methylated markers amongst cytogenetic risk groups of acute myeloid leukemia.HEXB/Hexosaminidase B Protein medchemexpress Epigenetics. 2015;ten(6):526sirtuininhibitor5. Unoki M, Brunet J, Mousli M. Drug discovery targeting epigenetic codes: the wonderful possible of UHRF1, which links DNA methylation and histone modifications, as a drug target in cancers and toxoplasmosis. Biochem Pharmacol. 2009;78(ten):1279sirtuininhibitor8. Cheng X, Blumenthal RM.Noggin Protein MedChemExpress Introduction piphanies in epigenetics. Prog Mol Biol Transl Sci. 2011;101:1sirtuininhibitor1. Alhosin M, Sharif T, Mousli M, Etienne-Selloum N, Fuhrmann G, Schini-Kerth VB, Bronner C. Down-regulation of UHRF1, linked with re-expression of tumor suppressor genes, is usually a widespread feature of natural compounds exhibiting anti-cancer properties.PMID:24670464 J Exp Clin Cancer Res. 2011;30:41. Bostick M, Kim JK, Esteve PO, Clark A, Pradhan S, Jacobsen SE. UHRF1 plays a role in keeping DNA methylation in mammalian cells. Science. 2007; 317(5845):1760sirtuininhibitor. Achour M, Jacq X, Ronde P, Alhosin M, Charlot C, Chataigneau T, Jeanblanc M, Macaluso M, Giordano A, Hughes AD, et al. The interaction with the SRA domain of ICBP90 with a novel domain of DNMT1 is involved within the regulation of VEGF gene expression. Oncogene. 2008;27(15):2187sirtuininhibitor7. Achour M, Mousli M, Alhosin M, Ibrahim A, Peluso J, Muller CD, Schini-Kerth VB, Hamiche A, Dhe-Paganon S, Bronner C. Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1. Biochem Biophys Res Commun. 2013;430(1):208sirtuininhibitor2. Bashtrykov P, Jankevicius G, Jurkowska RZ, Ragozin S, Jeltsch A. The UHRF1 protein stimulates the activity and specificity of the upkeep DNA methyltransferase DNMT1 by an allosteric mechanism. J Biol Chem. 2014;289(7):4106sirtuininhibitor5. Al-Kaabi A, van Bockel LW, Pothen AJ, Willems SM. p16INK4A and p14ARF gene promoter hypermethylation as prognostic biomarker in oral and oropharyngeal squamous cell carcinoma: a review. Dis Markers. 2014;2014:260549. Wang F, Yang YZ, Shi CZ, Zhang P, Moyer MP, Zhang HZ, Zou Y, Qin HL. UHRF1 promotes cell growth and metastasis by means of repression of p16(ink(4)a) in colorectal cancer. Ann Surg Oncol. 2012;19(eight):2753sirtuininhibitor2. Daskalos A, Oleksiewicz U, Filia A, Nikolaidis G, Xinarianos G, Gosney JR, Malliri A, Field JK, Liloglou T. UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer. Cancer. 2011;117(5):1027sirtuininhibitor7. Zhou L, Shang Y, Jin.
