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Product Name :
Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv)

synonym :

productDescription :
Enfortumab vedotin-ejfv is an ADC consisting of a Nectin-4-directed antibody and Monomethyl auristatin E (MMAE) , suitable for adult patients with locally advanced or metastatic urothelial carcinoma, or who have received programmed cell death protein 1 (PD-1) inhibitor or programmed cell death ligand 1 (PD-L1) inhibitor therapy or neoadjuvant/adjuvant platinum-based chemotherapy for locally advanced or metastatic cancer.

molecularWeight :
143.9 kDa

endotoxin :
<0.01 EU/ug

purity :
>95% as determined by SDS-PAGE.

formulation :
100 mM Pro-Ac 20mM Arg pH 5.0

storage :
-80°C for 2 years under sterile conditions;-20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.

reactivity :
Human, Mouse, Cynomolgus [USRE48389E1]

concentration :
5.6 mg/mL

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Ubiquitin Ligase- ubiquitin-ligase