Ipriflavone
Ipriflavone is a synthetic isoflavone that exhibits anti-osteoporotic, anti-resorptive, and cytoprotective activities. In animal models of low Ca2+ diet, ipriflavone decreases bone resorption and increases bone density and volume. In vitro, this compound protects against cyclophosphamide-induced DNA damage.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18931684
| Cas No. |
35212-22-7 |
|---|---|
| Purity |
≥98% |
| Formula |
C18H16O3 |
| Formula Wt. |
280.32 |
| Chemical Name |
7-(1-Methylethoxy)-3-phenyl-4H-1-benzopyran-4-one |
| IUPAC Name |
3-phenyl-7-propan-2-yloxychromen-4-one |
| Synonym |
Iprosten; Osten; Osteofix; Yambolap |
| Melting Point |
115-117°C |
| Solubility |
Poor solubility in water. |
| Appearance |
White Crystal Powder |
Lv WT, Yang YH, Ma LQ, et al. Ipriflavone reverses the adverse effects of a low-calcium diet on the histology of the tibia in caged layers. Br Poult Sci. 2014;55(2):207-14. PMID: 24404906.
Delarmelina JM, Dutra JC, Batitucci Mdo C. Antimutagenic activity of ipriflavone against the DNA-damage induced by cyclophosphamide in mice. Food Chem Toxicol. 2014 Mar;65:140-6. PMID: 24389340.
