BAM-12P
Bovine adrenal medulla 12 peptide (BAM-12P) is a cleavage product of proenkephalin that binds κ-opioid receptors (κORs). BAM-12P plays a role in antinociceptive signaling.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18843004
| Cas No. |
75513-71-2 |
|---|---|
| Purity |
≥95% |
| Formula |
C62H97N21O16S |
| Formula Wt. |
1424.66 |
| IUPAC Name |
2-[[1-[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]pentanedioic acid |
| Synonym |
Bovine adrenal medulla 12 peptide |
Davis TP, Hoyer GL, Davis P, et al. Proenkephalin A-derived peptide E and its fragments alter opioid contractility in the small intestine. Eur J Pharmacol. 1990 Dec 4;191(3):253-61. PMID: 2086244.
Mizuno K, Minamino N, Kangawa K, et al. A new endogenous opioid peptide from bovine adrenal medulla: isolation and amino acid sequence of a dodecapeptide (BAM-12P). Biochem Biophys Res Commun. 1980 Aug 29;95(4):1482-8. PMID: 7417331.
