Pep-1 Peptide
Pep-1 Peptide Pep-1 is a cell-penetrating peptide used to carry large conjugated structures across cell membranes. Pep-1 inhibits low molecular weight hyaluronan binding to toll-like receptor 4 (TLR4) and other…
2017
Pentoxifylline
Pentoxifylline Pentoxifylline is a xanthine derivative that exhibits anti-inflammatory, cardioprotective, antithrombotic, analgesic, and anti-fibrotic activities. Pentoxifylline is clinically used to treat intermittent claudication, peripheral vascular disease, and neuropathies. Pentoxifylline is…
Pentagastrin
Pentagastrin Pentagastrin is a synthetic polypeptide that stimulates gastric acid secretion on the gastrointestinal tract in a cholinergic signaling-dependent manner. Pentagastrin inhibits motilin-induced contractions in the stomach in animal models.…
Penitrem A
Penitrem A Penitrem A is a neuroactive mycotoxin initially produced by species of Penicillum. Penitrem A exhibits tremorgenic activity. In vitro and in vivo, penitrem A inhibits Ca2+/voltage-sensitive K+ (BK)…
Pelitinib
Pelitinib Pelitinib is an irreversible EFGR inhibitor that exhibits anticancer chemotherapeutic benefit in the treatment of non-small cell lung cancer (NSCLC) and other solid tumor cancers. In vitro, pelitinib inhibits…
Paroxetine Hydrochloride Hemihydrate
Paroxetine Hydrochloride Hemihydrate Paroxetine is a SSRI that primarily inhibits activity of the 5-HT transporter (SERT) but also displays some affinity for the norepinephrine transporter (NET) and for muscarinic acetylcholine…
Parathyroid Hormone-Related Protein (1-34), human/rat
Parathyroid Hormone-Related Protein (1-34), human/rat PTH (parathyroid hormone)-related protein (PTH-RP) binds the PTH1 receptor and exhibits anti-osteoporotic, anti-angiogenic, and pro-fibrotic activities. PTH (1-34) is an endogenous peptide that is clinically…
Pantoprazole
Pantoprazole Pantoprazole is an H+/K+ ATPase inhibitor that exhibits antacid, anti-parasitic, and anticancer chemotherapeutic activities. Pantoprazole is clinically used to treat gastroesophageal reflux disease (GERD), although its inhibition of ROCK-2…
Pancuronium Bromide
Pancuronium Bromide Pancuronium is a reversible, competitive inhibitor of post-synaptic nicotinic acetylcholine receptors (nAChRs) that acts as a non-depolarizing neuromuscular junction (NMJ) blocker. When used clinically, pancuronium induces skeletal muscle…
Pancreatic Polypeptide, human
Pancreatic Polypeptide, human Pancreatic polypeptide is an endogenous neuropeptide Y-family hormone that exhibits anorexigenic activity. Pancreatic polypeptide binds the Y4 receptor to decrease food intake, increase locomotor activity, and stimulate…