PFI-1
PFI-1 PFI-1 is an inhibitor of BET bromodomains (BRDs) that prevents the association of BET with histones; it acts as an acyl-lysine (Kac) mimetic inhibitor, binding the Kac site of…
2017
PF-06447475
PF-06447475 PF-06447475 inhibits leucine-rich repeat kinase 2 (LRRK2), exhibiting neuroprotective activity. In animal models of Parkinson’s disease, this compound suppresses neuroinflammation and neurodegeneration. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18953056 Cas No. 1527473-33-1 Formula…
PF-04217903
PF-04217903 PF-04217903 is a triazolopyrazine inhibitor of c-MET that displays anticancer chemotherapeutic and anti-metastatic activities. PF-04217903 inhibits cell proliferation, invasion, and migration as well as tumor growth in various cancer…
Perifosine
Perifosine Perifosine is an alkylphospholipid analog that exhibits anticancer chemotherapeutic and anti-inflammatory activities. Perifosine directly inhibits Akt by binding at multiple sites. In macrophages, perifosine inhibits LPS-induced increases in TNF-α…
Peptide YY, pig
Peptide YY, pig Peptide YY is an endogenous neuropeptide Y-related peptide that activates Y1 and Y2 receptors. Peptide YY is an appetite-regulating hormone secreted from the gastrointestinal tract that exhibits…
Peptide YY, human
Peptide YY, human Peptide YY is an endogenous neuropeptide Y-related peptide that activates Y1 and Y2 receptors. Peptide YY is an appetite-regulating hormone secreted from the gastrointestinal tract that exhibits…
Peptide YY (3-36), human
Peptide YY (3-36), human Peptide YY is an endogenous neuropeptide Y-related peptide that activates Y1 and Y2 receptors. Peptide YY is an appetite-regulating hormone secreted from the gastrointestinal tract that…
Peptide T
Peptide T Peptide T is an octapeptide fragment of the V2 region of HIV-1 glycoprotein gp120. Peptide T exhibits anti-inflammatory activity, decreasing inflammation and acting as a potential treatment for…
Peptide Standard 1
Peptide Standard 1 For use in amino acid analysis. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18952921 Purity ≥95% Formula C98H144N25O26S2 Formula Wt. 2152.52 PF 04691503
Pepstatin
Pepstatin Pepstatin is a peptide originally found in Actinomyces; it inhibits aspartyl proteases such as pepsin and cathepsins D and E. Pepstatin may inhibit RANKL-induced osteoclast differentiation and phosphorylation of…