Pancreatic Polypeptide, chicken Pancreatic polypeptide is an endogenous neuropeptide Y-family hormone that exhibits anorexigenic activity. Pancreatic polypeptide binds the Y4 receptor to decrease food intake, increase locomotor activity, and stimulate…
Pancreastatin, pig Pancreastatin is an endogenous peptide derived from chromogranin-A that regulates insulin action, inhibiting insulin secretion and increasing glucagon secretion. Pancreastatin binds and inhibits GRP78, decreasing insulin-stimulated glucose uptake…
Panaxatriol Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities. Panaxatriol increases expression of heme oxygenase 1 (HO-1) and…
Panaxadiol Panaxadiol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. Panaxadiol inhibits Ca2+ channels, decreasing channel open time and…
Pamidronate Disodium Pentahydrate Pamidronate is a bisphosphonate that exhibits anti-resorptive and anti-osteoporotic activities. Pamidronate is clinically used to prevent injury- or chemotherapy-induced bone loss. Clinically, pamidronate increases muscle fiber, bone…
Palmitoyl-L-carnitine Palmitoyl-L-carnitine is a long chain acylcarnitine that is involved in fatty acid metabolism. This compound is a substrate used to stimulate mitochondrial respiration and to study mitochondrial function in…
Palmitoyl-D,L-carnitine Palmitoyl-D,L-carnitine is a long chain acylcarnitine that is involved in fatty acid metabolism; it may be used as a substrate in the simulation of mitochondrial respiration. Palmitoyl-D,L-carnitine inhibits PKC…
Palmatine Chloride Hydrate Palmatine is an isoquinoline alkaloid found in Corydalis, Phellodendron, Enantia, and other plants. Palmatine exhibits sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities. Palmatine binds hemoglobin…
Paliperidone Paliperidone is an antipsychotic compound that inhibits D2 receptors and 5-HT2A receptors and is used to treat schizophrenia. Paliperidone also attenuates epinephrine- and serotonin-induced platelet aggregation. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18952469…
Palbociclib Isethionate Palbociclib is an inhibitor of CDK4 and CDK6 that displays anticancer chemotherapeutic and nephroprotective activities; it is currently in clinical trials as a potential treatment for breast cancer.…