Palbociclib Hydrochloride Palbociclib is an orally bioavailable selective inhibitor of CDK4 and CDK6, kinases that regulate cell cycle progression. This compound exhibits anticancer chemotherapeutic activity in a variety of models,…
Paeonol Paeonol was originally found in species of Paeonia, Arisaema, and Dioscorea. Paeonol exhibits anti-inflammatory, analgesic, neuromodulatory, vasodilatory, anticancer, anti-atherosclerotic, and anti-angiogenic activities. Paeonol inhibits carrageenan-induced thermal hyperalgesia and decreases…
Paeoniflorin Paeoniflorin is found in Paeonia; it exhibits anti-inflammatory, antioxidative, neuromodulatory, antidepressant, analgesic, and anticancer chemotherapeutic activities. In animal models of DSS-induced colitis, paeoniflorin decreases expression of toll-like receptor 4…
Paclitaxel, from Taxus yunnanensis Paclitaxel is a diterpene compound found in Taxus yunnanensis that exhibits anticancer chemotherapeutic and anti-angiogenic activities. Paclitaxel induces tubulin polymerization, forming stable but nonfunctional microtubules; it…
P7C3A20 P7C3A20 is a fluorinated aminopropyl carbazole; it is a more active analog of P7C3 that also exhibits antidepressant, cognition enhancing, and neuroprotective activities. In animal models of traumatic brain…
P7C3 P7C3 is an aminopropyl carbazole that displays neuroprotective, antidepressant, and cognition enhancing activities, particularly in models of Parkinson’s disease and amyotrophic lateral sclerosis (ALS). P7C3 promotes neurogenesis in vivo…
P75-TNFR Peptide P75-TNFR is a peptide fragment of the P75 tumor necrosis factor (TNF) receptor. This receptor is involved in post-injury protective signaling and mediates expression of plasminogen activator inhibitor…
P55-TNFR Peptide P55-TNFR is a peptide fragment of the P55 tumor necrosis factor (TNF) receptor. This receptor is involved in insulin sensitivity, cell death signaling, and the development of atherosclerosis.…
P1 Peptide P1 is an octapeptide that suppresses binding of EGFR to the Src homology region (Sh2) of phospholipase C-γ (PLCγ). References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18952220 Purity ≥95% Formula C39H63N11O13 Formula Wt.…
p-Xyleneselenocyanate p-Xyleneselenocyanate is a synthetic derivative of selenocyanate. Derivatives of selenocyanate exhibit antioxidative, anticancer, and anti-parasitic activities. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18952135 Cas No. 85539-83-9 Purity ≥99% Formula C10H8N2Se2 Formula Wt. 314.10…