PIK-294
PIK-294 PIK-294 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K and less sensitive to p110α PI3K. References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18954370 Cas No. 900185-02-6 Purity ≥98% Formula C28H23N7O2…
PIK-294 PIK-294 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K and less sensitive to p110α PI3K. References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18954370 Cas No. 900185-02-6 Purity ≥98% Formula C28H23N7O2…
PIK-75 Hydrochloride PIK-75 is an inhibitor of p110α PI3K that exhibits anticancer and anti-inflammatory activities. In breast cancer cells, PIK-75 inhibits cell motility and adhesion in vitro and in vivo.…
PIK-93 PIK-93 is an inhibitor of PI3K that exhibits some selectivity for p110α and p110γ. PIK-93 also inhibits PI4KIIIβ, a phosphatidylinositol enzyme similar to PI3K. PIK-93 decreases translocation of transient…
Pimecrolimus Pimecrolimus is a calcineurin inhibitor that exhibits immunosuppressive, anti-inflammatory, and antinociceptive activities. Pimecrolimus prevents calcineurin from dephosphorylating nuclear factor of activated T cells (NF-AT), inhibiting T cell signaling; this…
Pimobendan Pimobendan is a cardiovascular drug commonly used to treat congestive heart failure, dilated cardiomyopathy, and chronic valvular heart disease in veterinary medicine. This compound exhibits vasodilatory and antithrombotic activities,…
Pioglitazone Hydrochloride Pioglitazone is a thiazolidinedione that acts as an agonist at PPARα/γ receptors and also binds mitoNEET, a mitochondrial protein involved in energy homeostasis. Pioglitazone exhibits anti-diabetic, antacid, antidepressant,…
Pipemidic Acid Pipemidic acid is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase; it exhibits antibacterial activity. Pipemidic acid also inhibits ATP-sensitive K+ channels, inducing insulin release in vitro, suggesting…
Piperacillin Piperacillin is a β-lactam antibiotic that inhibits bacterial cell wall synthesis. Piperacillin is often paired with a β-lactamase inhibitor such as Tazobactam, improving its antibacterial efficacy. References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/1895456…
Piperacillin Sodium Piperacillin is a β-lactam antibiotic that inhibits bacterial cell wall synthesis. Piperacillin is often paired with a β-lactamase inhibitor such as Tazobactam, improving its antibacterial efficacy. References PubMed…
Piperine Piperine is an alkaloid originally found in several species of black and long peppers. Piperine exhibits anticancer, anti-diabetic, immunomodulatory, antioxidative, anti-inflammatory, cognition enhancing, and neuroprotective activities. In prostate cancer…