Piperlongumine Piperlongumine is found in several species of the Piper plant and displays many beneficial characteristics, including antithrombotic, anti-inflammatory, anti-atherosclerotic, and chemotherapeutic activities. Piperlongumine directly inhibits thromboxane A2 (TxA2) receptors,…
Piperlonguminine Piperlonguminine is found in several species of the Piper plant and displays many beneficial characteristics, including antithrombotic, anti-inflammatory, anti-hyperlipidemic, antibacterial, anti-parasitic, antifungal, neuroprotective, and anticancer chemotherapeutic activities. In animal…
Pirarubicin Pirarubicin is an anthracycline derivative of adriamycin that is clinically co-administered with other anticancer chemotherapeutics in the treatment of a variety of cancers. Pirarubicin is a DNA intercalator that…
Pirfenidone Pirfenidone is an anti-fibrotic and anti-inflammatory compound that is used to treat pulmonary fibrosis. Pirfenidone decreases fibroblast production, suppresses expression of TNF-α and IL-1β, and inhibits TGF-β-induced stimulation of…
Piroxicam Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, antipyretic, neuroprotective, anticancer, and chemopreventive activities. Piroxicam inhibits COX-1 and COX-2. Cu(II) complexes of piroxicam bind GC sequences…
Pitavastatin Calcium Pitavastatin is an inhibitor of HMG-CoA reductase that is used to treat atherosclerosis in clinical settings. Pitavastatin exhibits anti-atherosclerotic, anti-inflammatory, immunomodulatory, anti-hyperlipidemic, and antioxidative activities. In vitro and…
Pituitary Adenylate Cyclase-activating Peptide (6-38), human/sheep/rat Pituitary adenylate cyclase-activating polypeptide (PACAP) is an endogenous peptide that stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP) regulate immune…
Pituitary Adenylate Cyclase-activating Polypeptide (1-27), human, sheep, rat Pituitary adenylate cyclase-activating polypeptide (PACAP) is an endogenous peptide that stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP)…
Pituitary Adenylate Cyclase-activating Polypeptide (1-38), frog Pituitary adenylate cyclase-activating polypeptide (PACAP) is an endogenous peptide that stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP) regulate immune…
Pituitary Adenylate Cyclase-activating Polypeptide (1-38), human, sheep, rat Pituitary adenylate cyclase-activating polypeptide (PACAP) is an endogenous peptide that stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP)…