Puromycin Dihydrochloride Puromycin is an aminonucleoside antibiotic compound originally produced by Streptomyces alboniger. Puromycin displays antibacterial activity through inhibition of ribosomal protein translation; it resembles the 3’ end of tRNA…
Purpurin Purpurin is an anthraquinone found in madder root that is occasionally used as a pigment dye. Purpurin also exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. In vivo and in…
Purvalanol A Purvalanol A is a purine derivative anticancer compound that inhibits cyclin-dependent kinases (CDKs). Purvalanol A induces cell cycle arrest and apoptosis in breast cancer cells and is clinically…
Puupehenone Puupehenone is a sesquiterpene found in marine sponges that displays some antioxidative and antiangiogenic activities. In separate cellular models, puupehenone inhibits cell growth and also decreases radical generation by…
PX-866 PX-866 is a wortmannin analog that inhibits PI3K, exhibiting anticancer chemotherapeutic and anti-angiogenic activities. PX-866 is currently in clinical trials as a standalone or combination therapy in the treatment…
Pyr-GR-pNA Pyr-Gly-Arg-pNA is a fluorogenic peptide substrate that is used to measure activity of serine proteases such as kallikrein 8 and tryptase. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18955670 Purity ≥98% Formula C19H26N8O6 Formula…
Pyrantel Pamoate Pyrantel pamoate is a mixture of pyrantel, a thiophene, and pamoic acid. This combination exhibits anti-parasitic/anti-helminthic activities. Pyrantel pamoate acts as a depolarizing neuromuscular junction blocker, activating nicotinic…
Pyrazinamide Pyrazinamide is a nicotinamide analog prodrug that exhibits antibiotic activity, inhibiting bacterial fatty acid synthetase I. Pyrazinamide displays antibacterial efficacy against both active and dormant bacteria, disrupting cell membranes,…
Pyridostatin Hydrochloride Pyridostatin is a G-quadruplex ligand that induces conformation changes in telomere-G-quadruplex complexes and stimulates double-stranded DNA breakage; it also alters telomere function. Pyridostatin displays antiviral and anticancer activities.…
Pyridoxine Hydrochloride Pyridoxine is a derivative of vitamin B6. In a clinical setting, pyridoxine decreases photosensitivity in subjects with erythropoietic protoporphyria. Pyridoxine exhibits antioxidative activity, inhibiting oxidized LDL-induced generation of…