Podophyllotoxin Podophyllotoxin is a non-alkaloid lignan found in species of Podophyllum that exhibits anticancer and antiviral activities. Podophyllotoxin displays antimitotic action, binding tubulin and inhibiting mitotic spindle formation. Derivatives of…
Polydatin Polydatin is a resveratrol-related glucoside originally found in Polygonum cuspidatum. Polydatin exhibits anticancer, anti-inflammatory, antioxidative, and anti-allergic activities. In lung cancer cells, polydatin downregulates expression of cyclin D1 and…
Prasugrel Prasugrel is a third generation thienopyridine antithrombotic that irreversible inhibits the ADP P2Y12 receptor, inhibiting platelet aggregation. Prasugrel is a prodrug; it undergoes rapid hydrolysis and oxidation in vivo…
Procaterol Hydrochloride Procaterol is an agonist at β2-adrenergic receptors that exhibits anti-inflammatory, anti-asthma, and bronchodilatory activities. Procaterol is used to treat asthma. In animal models, procaterol suppresses anaphylactic reactions. In…
Protodioscin Protodioscin is a saponin originally found in the rhizomes of several species of Dioscorea. Protodioscin exhibits cardioprotective, anti-hyperlipidemic, and anticancer activities. Protodioscin increases activities of the Na+/K+ ATPase and…
Protopanaxatriol Protopanaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits antihypertensive, neuromodulatory, and antioxidative activities. Protopanaxatriol prevents breakdown of vitamin D3 and inhibits GABA-A and…
Protopine Protopine is an isoquinoline alkaloid originally found in a variety of sources, including species of Corydalis and Papavera. Protopine exhibits analgesic, anti-inflammatory, anticancer, antioxidative, neuroprotective, and anti-parasitic/anti-helminthic activities. Protopine…
Proxymetacaine Hydrochloride Proxymetacaine is a topical anesthetic that is commonly used for ocular anesthesia or analgesia. Like other anesthetics, proxymetacaine may drive its function from inhibition of voltage-gated Na+ channels.…
Prulifloxacin Prulifloxacin is a fluoroquinolone antibiotic with broad spectrum antibacterial activity against Escherichia, Proteus, Staphylococcus, Streptococcus, and Haemophilus. Like other fluoroquinolones, prulifloxacin inhibits DNA gyrase and topoisomerase IV, preventing DNA…
Pseudoginsenoside F11 Pseudoginsenoside F11 is a saponin originally found in species of Panax (ginseng) that exhibits anti-inflammatory, anti-diabetic, neuroprotective, cognition enhancing, and antioxidative activities. Pseudoginsenoside F11 inhibits LPS-stimulated expression of…