Indirubin
Indirubin Indirubin is a bisindole isomer of indigo found in Indigo naturalis. Indirubin exhibits anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities. In vivo, indirubin decreases levels of IgE and production of…
Ubiquitin Ligase- ubiquitin-ligase
Interleukin-6 Receptor Fragment
Interleukin-6 Receptor Fragment This peptide fragment of the soluble IL-6 receptor binds IL-6 weakly but does not display significant downstream signaling effects. This peptide may be used to measure presence…
Iohexol
Iohexol Iohexol is a low osmolarity contrast agent used to visualize vasculature in coronary imaging procedures. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18931626 Cas No. 66108-95-0 Purity ≥98% Formula C19H26I3N3O9 Formula Wt. 821.14 Chemical…
Ionomycin Calcium
Ionomycin Calcium Ionomycin is a polyether antibiotic that acts as a Ca2+ ionophore, modulating intracellular Ca2+ signaling to increase cytosolic Ca2+ levels. Ionomycin modulates Ca2+ signaling across many cell types…
Ionomycin, Free Acid
Ionomycin, Free Acid Ionomycin is a polyether antibiotic that acts as a Ca2+ ionophore, modulating intracellular Ca2+ signaling to increase cytosolic Ca2+ levels. Ionomycin modulates Ca2+ signaling across many cell…
IOX2
IOX2 IOX2 is an inhibitor of prolyl hydroxylase that activates HIF-1α and as a result, exhibits pro-angiogenic activity. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18931681 Cas No. 931398-72-0 Purity ≥98% Formula C19H16N2O5 Formula Wt.…
IPI-145
IPI-145 IPI-145 is an inhibitor of p110δ PI3K that exhibits anticancer chemotherapeutic, immunosuppressive, and anti-inflammatory activities. In clinical trials, IPI-145 displays potential benefit in the treatment of chronic lymphocytic leukemia…
Ipriflavone
Ipriflavone Ipriflavone is a synthetic isoflavone that exhibits anti-osteoporotic, anti-resorptive, and cytoprotective activities. In animal models of low Ca2+ diet, ipriflavone decreases bone resorption and increases bone density and volume.…
Irbesartan
Irbesartan Irbesartan is an angiotensin II type 1 (AT1) receptor inhibitor that also activates PPARγ receptors; it exhibits antihypertensive, cardioprotective, and anti-hyperlipidemic activities. In angiotensin-converting enzyme 2 (ACE2)-deficient mice, irbesartan…
Irinotecan
Irinotecan Irinotecan is an analog of camptothecin that is used clinically to treat colon and ovarian cancers, among others. Irinotecan exhibits anticancer chemotherapeutic, anti-angiogenic, and immunosuppressive activities. Irinotecan inhibits DNA…