2-Hydroxyflutamide 2-Hydroxyflutamide is a non-steroidal anti-androgen that inhibits the androgen receptor. 2-Hydroxyflutamide exhibits anti-resorptive and anticancer activity. In osteoblasts, 2-hydroxyflutamide inhibits production of IL-6 and activation of NF-κB. In prostate…
2-Hydroxyestradiol 2-Hydroxy estradiol (2-OH E2) is a cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. 2-OH E2 exhibits anti-inflammatory, neuroprotective, mitogenic, and potentially anti-angiogenic activities. In vitro,…
2-Epi-16-deoxysarcophine 2-Epi-16-deoxysarcophine is a marine cembranoid found in Red Sea soft coral Sarcophyton glaucum; it exhibits anticancer potential, inhibiting metastasis in melanoma cells. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18832076 Purity ≥98% Formula C20H30O2…
2-Deoxy-D-glucose 2-deoxy-D-glucose inhibits glucose metabolism and is used as a biomarker of glucose metabolism, hypoxia, and angiogenesis in a variety of models and cell types, including neurotoxicity, cancer, and autoimmune…
2-(1,8-Naphthyridin-2-yl)phenol This naphthalene exhibits anticancer activity; in fibrosarcoma and breast cancer cells, it increases expression of STAT1 and IFN regulatory factor 1 and enhances the ability of IFNγ to inhibit…
18β-Glycyrrhetinic Acid 18β-Glycyrrhetinic Acid (enoxolone) is a triterpene glycoside found in Glycyrrhiza that exhibits anti-hyperlipidemic, anti-obesity, anti-inflammatory, anticancer, and anti-metastatic activities. Enoxolone is commercially used as a flavorant. Enoxolone inhibits…
17α-Hydroxyprogesterone Caproate 17α-Hydroxyprogesterone is a synthetic steroid hormone that displays anti-estrogenic activity; it is clinically used to prevent recurrent preterm birth in pregnant females. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1883197 Cas No. 630-56-8…
17-Allylaminogeldanamycin Geldanamycin derivative 17-AAG is an inhibitor of heat shock protein 90 (HSP90) that exhibits anti-inflammatory, anticancer chemotherapeutic, and antiviral activities. In endothelial cells, 17-AAG induces degradation of IκBα, attenuating…
16-Oxokahweol This compound is a synthetic derivative of kahweol, which is found in coffee. Like its parent compound, 16-oxokahweol may act induce phase II enzymes and may exhibit anticancer, chemopreventive,…
15-Acetyl-deoxynivalenol 15-acetyl deoxynivalenol (15-A-DON) a type A trichothecene mycotoxin initially produced by species of Fusarium. 15-A-DON is typically found in grains used for livestock feed as well as human consumption,…