2-(1,8-Naphthyridin-2-yl)phenol
This naphthalene exhibits anticancer activity; in fibrosarcoma and breast cancer cells, it increases expression of STAT1 and IFN regulatory factor 1 and enhances the ability of IFNγ to inhibit cell proliferation.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1883202
| Cas No. |
65182-56-1 |
|---|---|
| Purity |
≥98% |
| Formula |
C14H10N2O |
| Formula Wt. |
222.24 |
| IUPAC Name |
6-(1H-1,8-naphthyridin-2-ylidene)cyclohexa-2,4-dien-1-one |
| Appearance |
Red Crystals |
product targets : Haspin Kinase inhibitors
Lynch RA, Etchin J, Battle TE, et al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61. PMID: 17283162.
