GSK-2334470
GSK-2334470 GSK-2334470 is a selective inhibitor of PI3K that exhibits anticancer activity in in vitro models. GSK-2334470 inhibits T-loop phosphorylation of PI3K substrates SGK and S6K1, Akt and Akt substrates…
June 2017
GSK-2126458
GSK-2126458 GSK-2126458 is an ATP-competitive PI3K and mTOR inhibitor somewhat specific for the p110α isoform of PI3K. This compound exhibits anticancer chemotherapeutic activity, inhibiting growth in cellular models. GSK-2126458 is…
GSK-1070916
GSK-1070916 GSK-1070916 is an inhibitor of aurora kinases B and C (AurB/C) that exhibits anticancer chemotherapeutic activity. GSK-1070916 prevents AurB from phosphorylating serine 10 of histone H3. In cellular and…
GS-9973
GS-9973 GS-9973 is an imidazopyrazine inhibitor of Syk that is currently in clinical trials as a potential treatment for chronic lymphocytic leukemia (CLL). GS-9973 exhibits anticancer chemotherapeutic activity. In vitro,…
GS-967
GS-967 GS-967 inhibits voltage-gated Na+ channels, exhibiting antiepileptic, anticonvulsant, ant anti-arrhythmic activities. GS-967 decreases the cardiac late Na+ current. In vivo, this compound decreases seizure frequency and improves survival rates.…
Growth Hormone Releasing Peptide 2
Growth Hormone Releasing Peptide 2 Growth hormone releasing peptide 2 (GHRP-2) is a peptide that induces the release of growth hormone and secretion of cAMP, adrenocorticotropic hormone (ACTH), and insulin-like…
Growth Hormone Releasing Hexapeptide
Growth Hormone Releasing Hexapeptide Growth hormone releasing hexapeptide (GHRP-6) is a synthetic met-enkephalin analog that induces the release of growth hormone in vivo through binding of the ghrelin receptor. GHRP-6…
Growth Hormone Releasing Factor (1-44), human
Growth Hormone Releasing Factor (1-44), human Growth hormone releasing factor (GHRF or GHRH) is an endogenous peptide hormone that binds the GHRH receptor in the anterior pituitary, inducing the release…
Grape Skin Standards Kit
Grape Skin Standards Kit Grape Skin Standards Kit Contents: -Column: Cosmosil 2.5µ Cholester, 2.0 x 50 mm -1 mg Dihydroresveratrol -1 mg Emodin -1 mg Polydatin -1 mg Resveratrol -Standards…
Granuliberin R
Granuliberin R Granuliberin R is an amphiphillic antimicrobial peptide (AMP) originally found in amphibian skin. In mast cells, granuliberin R induces histamine release and increases K+ efflux. Granuliberin also inhibits…