Pimecrolimus Pimecrolimus is a calcineurin inhibitor that exhibits immunosuppressive, anti-inflammatory, and antinociceptive activities. Pimecrolimus prevents calcineurin from dephosphorylating nuclear factor of activated T cells (NF-AT), inhibiting T cell signaling; this…
PIK-93 PIK-93 is an inhibitor of PI3K that exhibits some selectivity for p110α and p110γ. PIK-93 also inhibits PI4KIIIβ, a phosphatidylinositol enzyme similar to PI3K. PIK-93 decreases translocation of transient…
PIK-75 Hydrochloride PIK-75 is an inhibitor of p110α PI3K that exhibits anticancer and anti-inflammatory activities. In breast cancer cells, PIK-75 inhibits cell motility and adhesion in vitro and in vivo.…
PIK-294 PIK-294 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K and less sensitive to p110α PI3K. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18954370 Cas No. 900185-02-6 Purity ≥98% Formula C28H23N7O2…
PIK-293 PIK-293 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K. PIK-293 is the parent compound of PIK-294. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18954321 Cas No. 900185-01-5 Purity ≥98% Formula…
Pidotimod Pidotimod is an immunostimulatory compound often used as an adjuvant. Pidotimod is clinically used to treat acute respiratory tract infections and stimulates both cellular and humoral immunity. In animal…
Picoplatin Picoplatin is an analog of cisplatin with a 2-methylpyridine ligand that displays anticancer chemotherapeutic activity. Picoplatin is used to treat non-small cell lung cancer (NSCLC) and is in clinical…
Piceatannol Piceatannol is a polyphenolic hydroxystilbene derivative of resveratrol with increased bioavailability and bioactivity compared to its parent compound. Piceatannol exhibits pro-angiogenic, anticancer, antioxidative, and anti-obesity properties. Piceatannol directly inhibits…
Phytic Acid, 40-50 wt% aqueous solution Phytic acid is a saturated cyclic acid used to store phosphorus in plants; it is non-digestible in humans but is occasionally used in cattle…
Phytanic Acid Phytanic acid is a fatty acid metabolite of chlorophyll that acts as a ligand of retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs) and is known to…