Pirfenidone Pirfenidone is an anti-fibrotic and anti-inflammatory compound that is used to treat pulmonary fibrosis. Pirfenidone decreases fibroblast production, suppresses expression of TNF-α and IL-1β, and inhibits TGF-β-induced stimulation of…
Pirarubicin Pirarubicin is an anthracycline derivative of adriamycin that is clinically co-administered with other anticancer chemotherapeutics in the treatment of a variety of cancers. Pirarubicin is a DNA intercalator that…
Piperlonguminine Piperlonguminine is found in several species of the Piper plant and displays many beneficial characteristics, including antithrombotic, anti-inflammatory, anti-hyperlipidemic, antibacterial, anti-parasitic, antifungal, neuroprotective, and anticancer chemotherapeutic activities. In animal…
Piperlongumine Piperlongumine is found in several species of the Piper plant and displays many beneficial characteristics, including antithrombotic, anti-inflammatory, anti-atherosclerotic, and chemotherapeutic activities. Piperlongumine directly inhibits thromboxane A2 (TxA2) receptors,…
Piperine Piperine is an alkaloid originally found in several species of black and long peppers. Piperine exhibits anticancer, anti-diabetic, immunomodulatory, antioxidative, anti-inflammatory, cognition enhancing, and neuroprotective activities. In prostate cancer…
Piperacillin Sodium Piperacillin is a β-lactam antibiotic that inhibits bacterial cell wall synthesis. Piperacillin is often paired with a β-lactamase inhibitor such as Tazobactam, improving its antibacterial efficacy. References PubMed…
Piperacillin Piperacillin is a β-lactam antibiotic that inhibits bacterial cell wall synthesis. Piperacillin is often paired with a β-lactamase inhibitor such as Tazobactam, improving its antibacterial efficacy. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1895456…
Pipemidic Acid Pipemidic acid is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase; it exhibits antibacterial activity. Pipemidic acid also inhibits ATP-sensitive K+ channels, inducing insulin release in vitro, suggesting…
Pioglitazone Hydrochloride Pioglitazone is a thiazolidinedione that acts as an agonist at PPARα/γ receptors and also binds mitoNEET, a mitochondrial protein involved in energy homeostasis. Pioglitazone exhibits anti-diabetic, antacid, antidepressant,…
Pimobendan Pimobendan is a cardiovascular drug commonly used to treat congestive heart failure, dilated cardiomyopathy, and chronic valvular heart disease in veterinary medicine. This compound exhibits vasodilatory and antithrombotic activities,…