Physcion Physcion is an anthraquinone originally found in several plant sources, including Microsporum, Psorospermum, Rhamnus, and Rheum. Physcion exhibits anticancer, antibiotic, and anti-inflammatory activities. In cervical carcinoma cells, physcion induces…
Physalaemin Physalaemin is an amphibian tachykinin neuropeptide. This peptide induces contractions in distal colon and esophageal longitudinal muscle in vivo through direct activation of smooth muscle cells and Ca2+ influx.…
Phyllomedusin Phyllomedusin is an amphibian tachykinin neuropeptide that activates neurokinin 1 (NK1) receptors. Phyllomedusin induces contractions in ileal longitudinal muscle and stimulates spasmogenic activity in stomach smooth muscle. References PubMed…
Phyllolitorin Phyllolitorin is a bombesin-related amphibian nonapeptide. Phyllolitorin induces contractions in urinary bladder smooth muscle and may play a role in lung branching morphogenesis. In mammals, phyllolitorin binds the gastrin-releasing…
PHT-427 PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC). References…
Phosphate Acceptor Peptide Phosphate acceptor peptide is a substrate of PKC and S6 kinase. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18954071 Purity ≥95% Formula C41H74N16O11 Formula Wt. 967.15 Appearance White to off white powder…
Phorbol-12,13-dibutyrate Phorbol 12,3-dibutyrate (PBDu) activates PKC and PKD and induces apoptosis and differentiation in leukemia cells. PBDu is carcinogenic. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18953766 Cas No. 37558-16-0 Purity ≥98% Formula C30H46O8 Formula…
Phorbol-12-myristate-13-acetate Phorbol-12-myristate-13-acetate (PMA) activates PKC and induces DNA damage. PMA exhibits pro-inflammatory, carcinogenic, and cytotoxic activities. This compound is often used in research models as a tumor promoter. References PubMed…
Phleomycin Phleomycin is a glycopeptide antibiotic that binds DNA but does not intercalate. Phleomycin is mutagenic and requires metal ions to induce double-stranded DNA breaks. This compound displays some antibacterial…
Phenylhexyl Isothiocyanate Isothiocyanates are compounds typically found in plants of the Brassicaceae family, including broccoli, cabbage, and radish. Isothiocyanates are best known for their antioxidative, anticancer chemotherapeutic, chemopreventive, anti-angiogenic, and…