AS-605240 AS-605240 is an inhibitor of p110δ PI3K that exhibits anti-inflammatory, immunosuppressive, and anti-diabetic activities. In animal models, AS-605240 inhibits the development of or reverses the progression of experimental autoimmune…
AS-604850 AS-604850 is an inhibitor of p110γ PI3K that exhibits anti-inflammatory and immunosuppressive activities. In animal models of experimental autoimmune encephalitis (EAE), AS-604850 decreases the number of leukocytes infiltrated into…
AS-252424 AS-252424 is an inhibitor of p110γ PI3K that exhibits anti-inflammatory activity. In animal models of peritoneal inflammation, AS-252424 decreases leukocyte recruitment. In vascular smooth muscle cells, AS-252424 decreases endothelin…
Arvanil Arvanil is an agonist at transient receptor potential vanilloid 1 (TRPV1) channels and cannabinoid 1 (CB1) receptors. Arvanil exhibits antidepressant, hypertensive, immunosuppressive, anti-inflammatory, antiemetic, and anticancer activities. Arvanil decreases…
Artemisinin Artemisinin is a sesquiterpene lactone originally found in Artemisia (wormwood); it is clinically used to treat malaria. Artemisinin exhibits anti-parasitic, antimalarial, cardioprotective, anticancer, and anti-inflammatory activities. This compound inhibits…
Artemether Artemether is a sesquiterpene lactone derived from Artemisia. Artemisinins such as artemether are best known for their antimalarial activity. Artemether exhibits anti-parasitic activity against Plasmodium, Leishmania, and Schistosoma. References…
ARRY-162 ARRY-162 is an orally bioavailable noncompetitive inhibitor of MEK1/2 and ERK that shows anticancer chemotherapeutic activity. Inhibition of MEK inhibits downstream signaling by IL-1, IL-6, and TNF. ARRY-162 inhibits…
Aristolochic Acids Standards Kit Aristolochic Acids Standards Kit Contents: -Column: Cosmosil 2.5µ Cholester, 2.0 x 50 mm -1 mg Aristolochic Acid A -1 mg Aristolochic Acid B -1 mg Aristolochic…
Aristolochic Acid C Aristolochic acid C is a carcinogenic compound found in Aristolochia and Radix that has commonly been used in traditional Chinese medicine. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18842464 Cas No. 4849-90-5…
Aristolochic Acid B Aristolochic acid B is a carcinogenic compound found in Aristolochia and Radix that has commonly been used in traditional Chinese medicine. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18842389 Cas No. 475-80-9…