Aristolochic Acid A
Aristolochic Acid A Aristolochic acid A is a carcinogenic compound found in Aristolochia and Radix that has commonly been used in traditional Chinese medicine. This compound inhibits phospholipase A2 (PLA2)…
June 2017
Aripiprazole
Aripiprazole Aripiprazole is a second generation atypical antipsychotic that also exhibits neuromodulatory, antidepressant, anxiolytic, antipsychotic, cognition enhancing, and antioxidative activities. Aripiprazole acts as a partial agonist at D2 receptors and…
Argipressin Acetate
Argipressin Acetate Arginine vasopressin peptide (argipressin) is endogenously produced through activation of renin-angiotensin signaling pathways. Argipressin binds vasopressin V1a, V1b, and V2 receptors and exhibits pressor activity, increasing blood pressure.…
Argatroban
Argatroban Argatroban is an antithrombotic/anticoagulant compound that inhibits thrombin. Argatroban is clinically used to treat thrombosis and acute coronary syndrome. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18842294 Cas No. 74863-84-6 Purity ≥98% Formula C23H36N6O5S…
Arformoterol Tartrate
Arformoterol Tartrate Arformoterol is the R,R enantiomer of formoterol. Arformoterol exhibits anti-inflammatory and anti-asthma activities, potentiating the effects of co-administered glucocorticoids in the treatment of asthma and chronic obstructive pulmonary…
Arenobufagin
Arenobufagin Arenobufagin is a bufanolide steroid found in the Argentine toad Bufo arenarum. This compound exhibits anticancer chemotherapeutic and anti-angiogenic properties, but is also cardiotoxic, inhibiting cardiovascular Na+/K+ pumps. In…
Arbutin
Arbutin Arbutin is a glycoside hydroquinone originally found in Bergenia and Arctostaphylos that inhibits tyrosinase. Arbutin decreases melanin production and is commercially used in skin-lightening products. Arbutin also inhibits phospholipase…
AR-A014418
AR-A014418 AR-A014418 is an inhibitor of GSK-3β that exhibits anticancer, analgesic, cognition enhancing, neuroprotective, and anti-inflammatory activities. AR-A014418 decreases cell viability and downregulates expression of splicing factors, Bcl-2, Bcl-xl, survivin,…
Aprotinin
Aprotinin Aprotinin is a polypeptide that exhibits anti-fibrinolytic (pro-coagulant) activity. Aprotinin inhibits serine proteases such as trypsin, chymotrypsin, plasmin, and kallikrein. Inhibiting these proteases prevents formation of Factor XIIa and…
Aprepitant
Aprepitant Aprepitant is an inhibitor of the tachykinin/neurokinin 1 (NK1) receptor that acts as an antiemetic or anti-nausea medicine. Aprepitant also exhibits some anticancer chemotherapeutic and anti-angiogenic benefit through its…