Veliparib Veliparib is an oral poly(ADP-ribose) polymerase (PARP) inhibitor that shows anticancer chemotherapeutic and anti-inflammatory activities. Veliparib crosses the blood-brain barrier with a 3:1 plasma:brain drug ratio. Inhibition of PARP…
Vemurafenib Vemurafenib is a first generation selective B-Raf inhibitor that has been approved for clinical use in treating unresectable or metastatic melanoma; it exhibits anticancer chemotherapeutic activity. Vemurafenib binds the…
Verapamil Hydrochloride Verapamil is an inhibitor of L-type voltage-gated Ca2+ channels that exhibits antihypertensive, anti-arrhythmic, and cardioprotective activities; it is classified as a class IV anti-arrhythmic. Verapamil treats hypertension and…
Veratridine Veratridine is an alkaloid from the plant Liliaceae that has been shown to exhibit synergistic anti-tumor effects in combination with chemotherapeutic drugs. It has been found to upregulate the…
Verbascoside Verbascoside is a phenylpropanoid found in a variety of species of Castilleja, Verbena, and Verbascum. Verbascoside displays anti-inflammatory, analgesic, antioxidative, and antithrombotic properties in a variety of cellular and…
Verruculogen Verruculogen is a mycotoxin initially produced by species of Aspergillus; it is considered a tremorgenic indole alkaloid and may induce development of neurological disorders. Verruculogen inhibits Ca2+-activated K+ (BK)…
Vesicular Stomatitis Virus Peptide Vesicular stomatitis virus (VSV) is an antigenic peptide fragment of VSV that binds the LDL receptor. VSV exhibits anticancer chemotherapeutic potential. VSV is used as a…
VGX-1027 VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling. In diabetic mice, VGX-1027 decreases synthesis of pro-inflammatory cytokines and improves glomerulosclerosis. In other animal models,…
Vidarabine Vidarabine is a long-acting antiviral originally found in the marine sponge Tethyra crypta. Vidarabine is an adenosine analog in which the D-ribose constituent is replaced by D-arabinose, preventing formation…
Vidarabine Monophosphate Vidarabine is a long-acting antiviral originally found in the marine sponge Tethyra crypta. Vidarabine is an adenosine analog in which the D-ribose constituent is replaced by D-arabinose, preventing…