Saikosaponin A Saikosaponin A is a triterpene saponin found in Bupleurum that exhibits anti-inflammatory, analgesic, neuromodulatory, anticancer, and immunosuppressive activities. Saikosaponin A decreases production of TNF-α, IL-1β, and IL-2 and…
Saikosaponin B1 Saikosaponin B1 is a saponin found in various plants, including Bupleurum, Heteromorpha, and Scrophularia. In vitro, saikosaponin B1 stimulates release of prostaglandin E2 (PGE2). References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18971310 Cas…
Saikosaponin B2 Saikosaponin B2 is a saponin found in various plants, including Bupleurum, Heteromorpha, and Scrophularia. Saikosaponin B2 exhibits antiviral activity, inhibiting viral attachment, penetration, and proliferation of coronavirus in…
Saikosaponin C Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities. In vitro, saikosaponin C increases cell growth, cell migration, and capillary tube formation.…
Sarafloxacin Hydrochloride Sarafloxacin is a fluoroquinolone antibiotic that inhibits topoisomerase IV and DNA gyrase. Sarafloxacin displays antibacterial activity against Mycobacterium, Escherichia, and several other bacteria. This compound is most often…
Sarafotoxin 6c Sarafotoxin 6C (S6C) is an isoform of a toxin found in the venom of Atractaspis engaddensis snakes. S6C acts as a peptide agonist at endothelin B (ET-B) receptors…
Sarcophine Sarcophine is a marine cembranoid diterpene found in the Red Sea soft coral Sarcophyton glaucum. Sarcophine and its synthetic derivative, sarcophine-diol, exhibit chemopreventive activity. In vivo, sarcophine inhibits skin…
Satraplatin Satraplatin is a platinum-based anticancer chemotherapeutic that is used in cisplatin-resistant cancers; like other platinum compounds, it forms DNA adducts and inhibits DNA repair. Satraplatin induces G2/M phase cell…
SB-431542 SB-431542 inhibits activin receptor-like kinases ALK4, ALK5, and ALK7; this inhibition leads to inhibition of activin and TGF-β signaling with no downstream effects on ERK, JNK, or MAPK. SB-431542…
Schisantherin A Schisantherin A is a dibenzocyclooctadiene originally found in Schisandra that exhibits anti-tussive, sedative, anti-inflammatory, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities. In macrophages, schisantherin A decreases LPS-induced expression…