Ritodrine Hydrochloride Ritodrine is a β2-adrenergic receptor agonist that exhibits tocolytic activity. Ritodrine is clinically used to prevent preterm labor, as it decreases prostanoid signaling and inhibits uterine contractility. Ritodrine…
Ritonavir Ritonavir is an HIV protease inhibitor that is commonly used as a component of highly active anti-retroviral therapy (HAART) in the treatment of HIV infection. Ritonavir exhibits antiviral, anti-angiogenic,…
Rivastigmine Tartrate Rivastigmine is an inhibitor of acetylcholinesterase (AChE) and butylcholinesterase (BChE) that is used clinically to treat dementia. Rivastigmine exhibits anti-cholinergic, anti-inflammatory, cognition enhancing and neuroprotective activities. In vivo,…
RKI-1447 RKI-1447 is an inhibitor of ROCK1/2 that exhibits anticancer chemotherapeutic activity. RKI-1447 also displays anti-metastatic potential, suppressing phosphorylation of MLC-2, MYPT-1, inhibiting formation of actin stress fibers, and preventing…
RN-486 RN-486 is an inhibitor of Bruton’s tyrosine kinase (Btk) that is currently in development as a potential treatment for rheumatoid arthritis; it exhibits anti-inflammatory, nephroprotective, and immunosuppressive activities. RN-486…
Ro 20-1724 Ro 20-1724 is a phosphodiesterase inhibitor that has been shown to enhance cognition in streptozocin treated rats. In addition to learning and memory improvements, Ro 20-1724 was also…
Ro 61-8048 Ro 61-8048 inhibits kynurenine 3-hydroxylase, displaying anti-inflammatory and neuromodulatory activities. Ro 61-8048 is used to study kynurenine signaling in embryonic brain development. In models of trypanosomiasis, this compound…
Rocuronium Bromide Rocuronium is an aminosteroid that exhibits anesthetic activity, inducing relaxation of skeletal muscle. Rocuronium is a non-depolarizing neuromuscular junction (NMJ) blocker that inhibits post-synaptic nicotinic acetylcholine receptors (nAChRs);…
Rofecoxib Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits COX-2; it exhibits anti-inflammatory, analgesic, antiepileptic/anticonvulsant, and chemopreventive activities but is no longer clinically administered. Rofecoxib inhibits the formation…
Rolipram Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18964309 Cas No.…