Ro 61-8048 Ro 61-8048 inhibits kynurenine 3-hydroxylase, displaying anti-inflammatory and neuromodulatory activities. Ro 61-8048 is used to study kynurenine signaling in embryonic brain development. In models of trypanosomiasis, this compound…
Rocuronium Bromide Rocuronium is an aminosteroid that exhibits anesthetic activity, inducing relaxation of skeletal muscle. Rocuronium is a non-depolarizing neuromuscular junction (NMJ) blocker that inhibits post-synaptic nicotinic acetylcholine receptors (nAChRs);…
Rofecoxib Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits COX-2; it exhibits anti-inflammatory, analgesic, antiepileptic/anticonvulsant, and chemopreventive activities but is no longer clinically administered. Rofecoxib inhibits the formation…
Rolipram Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18964309 Cas No.…
Romidepsin Romidepsin is a depsipeptide prodrug that inhibits histone deacetylases (HDACs). Romidepsin is currently in clinical trials as a potential treatment for T-cell lymphomas; it displays anticancer chemotherapeutic and antiviral…
Ropinirole Hydrochloride Ropinirole is an indoline agonist at D2/3 receptors that is clinically used to treat restless leg syndrome and Parkinson’s disease. Ropinirole prevents dopaminergic neuron damage and MPTP-induced changes…
Roscovitine Roscovitine is an inhibitor of CDKs (1, 2, 5, 7, 9, 12) and L-type Ca2+ channels; it exhibits anti-inflammatory and anticancer activities. Roscovitine resolves neutrophil-driven inflammation. In B-cell lymphoma…
Rosiglitazone Rosiglitazone is a thiazolidinedione insulin sensitizer that activates PPARγ, decreasing blood glucose and insulin levels. Rosiglitazone exhibits anti-diabetic, anti-inflammatory, antioxidative, anticancer, anti-angiogenic, antihypertensive, and anti-fibrotic activities. In vivo, rosiglitazone…
Rosiglitazone Maleate Rosiglitazone is a thiazolidinedione insulin sensitizer that activates PPARγ, decreasing blood glucose and insulin levels. Rosiglitazone exhibits anti-diabetic, anti-inflammatory, antioxidative, anticancer, anti-angiogenic, antihypertensive, and anti-fibrotic activities. In vivo,…
Rosmarinic Acid Rosemarinic acid is a caffeic acid ester found in many plants, including Melissa, Salvia, Ocimum, Rosmarinus, and Origanum. Rosemarinic acid exhibits antidepressant, neuroprotective, anti-inflammatory, anti-allergic, anti-angiogenic, anti-fibrotic, and…