Risedronate Sodium Hydrate Risedronate is a bisphosphonate that exhibits anti-osteoporotic, anti-resorptive, anti-parasitic, and antimalarial activities. Risedronate inhibits bone marrow adipogenesis, decreases activity of mTORC1, and suppresses activation of NF-κB in…
Risedronic Acid Risedronic acid is a bisphosphonate clinically used to strengthen bone; it exhibits anti-osteoporotic, anti-inflammatory, antinociceptive, anti-parasitic, and antibiotic activities. Risedronic acid inhibits bone marrow adipogenesis and suppresses RANKL…
Risperidone Risperidone is a benzisoxazole atypical antipsychotic that also exhibits antidepressant, anti-inflammatory, and neuroprotective activities. Risperidone acts as an antagonist at D2 receptors and 5-HT2A receptors and as an agonist…
RITA Reactivation of p53 and induction of tumor cell apoptosis (RITA) is an activator of p53 that exhibits anticancer chemotherapeutic and anti-angiogenic activities. In vivo, RITA downregulates expression of VEGF,…
Ritodrine Hydrochloride Ritodrine is a β2-adrenergic receptor agonist that exhibits tocolytic activity. Ritodrine is clinically used to prevent preterm labor, as it decreases prostanoid signaling and inhibits uterine contractility. Ritodrine…
Ritonavir Ritonavir is an HIV protease inhibitor that is commonly used as a component of highly active anti-retroviral therapy (HAART) in the treatment of HIV infection. Ritonavir exhibits antiviral, anti-angiogenic,…
Rivastigmine Tartrate Rivastigmine is an inhibitor of acetylcholinesterase (AChE) and butylcholinesterase (BChE) that is used clinically to treat dementia. Rivastigmine exhibits anti-cholinergic, anti-inflammatory, cognition enhancing and neuroprotective activities. In vivo,…
RKI-1447 RKI-1447 is an inhibitor of ROCK1/2 that exhibits anticancer chemotherapeutic activity. RKI-1447 also displays anti-metastatic potential, suppressing phosphorylation of MLC-2, MYPT-1, inhibiting formation of actin stress fibers, and preventing…
RN-486 RN-486 is an inhibitor of Bruton’s tyrosine kinase (Btk) that is currently in development as a potential treatment for rheumatoid arthritis; it exhibits anti-inflammatory, nephroprotective, and immunosuppressive activities. RN-486…
Ro 20-1724 Ro 20-1724 is a phosphodiesterase inhibitor that has been shown to enhance cognition in streptozocin treated rats. In addition to learning and memory improvements, Ro 20-1724 was also…