Paeoniflorin Paeoniflorin is found in Paeonia; it exhibits anti-inflammatory, antioxidative, neuromodulatory, antidepressant, analgesic, and anticancer chemotherapeutic activities. In animal models of DSS-induced colitis, paeoniflorin decreases expression of toll-like receptor 4…
Paeonol Paeonol was originally found in species of Paeonia, Arisaema, and Dioscorea. Paeonol exhibits anti-inflammatory, analgesic, neuromodulatory, vasodilatory, anticancer, anti-atherosclerotic, and anti-angiogenic activities. Paeonol inhibits carrageenan-induced thermal hyperalgesia and decreases…
Palbociclib Hydrochloride Palbociclib is an orally bioavailable selective inhibitor of CDK4 and CDK6, kinases that regulate cell cycle progression. This compound exhibits anticancer chemotherapeutic activity in a variety of models,…
Palbociclib Isethionate Palbociclib is an inhibitor of CDK4 and CDK6 that displays anticancer chemotherapeutic and nephroprotective activities; it is currently in clinical trials as a potential treatment for breast cancer.…
Paliperidone Paliperidone is an antipsychotic compound that inhibits D2 receptors and 5-HT2A receptors and is used to treat schizophrenia. Paliperidone also attenuates epinephrine- and serotonin-induced platelet aggregation. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18952469…
Palmatine Chloride Hydrate Palmatine is an isoquinoline alkaloid found in Corydalis, Phellodendron, Enantia, and other plants. Palmatine exhibits sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities. Palmatine binds hemoglobin…
Palmitoyl-D,L-carnitine Palmitoyl-D,L-carnitine is a long chain acylcarnitine that is involved in fatty acid metabolism; it may be used as a substrate in the simulation of mitochondrial respiration. Palmitoyl-D,L-carnitine inhibits PKC…
Palmitoyl-L-carnitine Palmitoyl-L-carnitine is a long chain acylcarnitine that is involved in fatty acid metabolism. This compound is a substrate used to stimulate mitochondrial respiration and to study mitochondrial function in…
Pamidronate Disodium Pentahydrate Pamidronate is a bisphosphonate that exhibits anti-resorptive and anti-osteoporotic activities. Pamidronate is clinically used to prevent injury- or chemotherapy-induced bone loss. Clinically, pamidronate increases muscle fiber, bone…
Panaxadiol Panaxadiol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. Panaxadiol inhibits Ca2+ channels, decreasing channel open time and…