Gastrin I, human
Gastrin I, human Gastrin I, like gastrin, acts as an agonist at the cholestocystokinin 2 (CCK2) receptor, exhibiting anorexigenic and gastrointestinal motility modulating activities. Gastrin is an endogenous peptide that…
Ubiquitin Ligase- ubiquitin-ligase
Gastrin Releasing Peptide, human
Gastrin Releasing Peptide, human Gastrin-releasing peptide (GRP) is an endogenous bombesin-like peptide that stimulates the release of gastrin by binding GRP receptors; it is involved in feeding behavior (acting as…
Gatifloxacin Sesquihydrate
Gatifloxacin Sesquihydrate Gatifloxacin is a fluoroquinolone antibiotic that inhibits DNA gyrase. Gatifloxacin exhibits antibacterial efficacy against Mycobacterium and Streptococcus, treating tuberculosis and pneumonia. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18926245 Cas No. 180200-66-2 Purity…
GDC-0349
GDC-0349 GDC-0349 is an ATP-competitive inhibitor of mTOR that exhibits anticancer chemotherpeutic activity. GDC-0349 displays pre-clinical efficacy in vitro and in vivo. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18926277 Cas No. 1207360-89-1 Purity ≥98%…
GDC-0449
GDC-0449 GDC-0449 is an inhibitor of Smo that prevents downstream hedgehog (Hh) signaling. GDC-0449 exhibits anticancer chemotherapeutic activity; it is currently approved to treat basal cell carcinoma and is in…
GDC-0623
GDC-0623 GDC-0623 is an inhibitor of MEK that prevents MEK-dependent B-Raf and KRAS signaling. GDC-0623 exhibits anticancer chemotherapeutic activity and is currently in clinical trials as a potential treatment for…
GDC-0879
GDC-0879 GDC-0879 is an orally bioavailable kinase inhibitor that exhibits anticancer chemotherapeutic activity in vitro and in vivo. GDC-0879 inhibits mutant (V600E) B-Raf, a mutation common to many types of…
GDC-0980
GDC-0980 GDC-0980 is an inhibitor of PI3K and mTORC1/2 that exhibits anticancer chemotherapeutic and anti-angiogenic activities. GDC-0980 inhibits cell growth in uterine serous carcinoma cells and decreases vascular density by…
Gefitinib
Gefitinib Gefitinib is an anticancer chemotherapeutic compound that inhibits mutant isoforms of EGFR. Across a variety of cancer cell lines, gefitinib increases poly(ADP)-ribose polymerase (PARP) cleavage and apoptosis, resulting in…
Geldanamycin
Geldanamycin Geldanamycin is an inhibitor of heat shock protein 90 (HSP90) that exhibits antiviral, neuroprotective, and anticancer activities. Geldanamycin decreases viral titers and inflammation in animal models of Chikungunya virus…