Formestane Formestane is a steroidal androgen substrate that inhibits aromatase. Formestane is clinically used to treat ER+ breast cancer, as it inhibits production of estrogens. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18925636 Cas No.…
Foscarnet Sodium Foscarnet is an antiviral compound that inhibits reverse transcriptase of HIV-1 and DNA polymerase of other viruses, including CMV and HSV. Inhibition of these enzymes prevents DNA synthesis…
Fosfomycin Calcium Fosfomycin is an antibiotic initially produced by Streptomyces that exhibits antibacterial, anti-parasitic, antimalarial, and nephroprotective activities. Fosfomycin is active against both gram positive and gram negative bacteria and…
Fosinopril Sodium Fosinopril is an inhibitor of angiotensin-converting enzyme (ACE) that exhibits antihypertensive and anti-atherosclerotic activities. Fosinopril is clinically used to treat congestive heart failure (CHF). In vivo, fosinopril decreases…
Fotemustine Fotemustine is a chloroethylnitrosourea that exhibits anticancer chemotherapeutic benefit. Fotemustine alkylates or induces cross-links in DNA, halting cell cycle progression at the G2/M phase and inhibiting DNA repair mechanisms.…
Fulvestrant Fulvestrant is an anti-endocrine compound that exhibits anticancer chemotherapeutic benefit in the treatment of estrogen receptor (ER)-positive breast cancer. Fulvestrant causes degradation of ERs and downregulates ER expression, inhibiting…
Fumonisin B1 Fumonisin B1 is a mycotoxin initially produced by Fusarium that is found as a contaminant in grain, maize, and grapes. Fumonisin B1 inhibits sphingosine acyltransferase, disrupting sphingolipid metabolism.…
Fumonisin B2 Fumonisin B2 is a mycotoxin initially produced by Fusarium that is found as a contaminant in grain, maize, and grapes. Fumonisin B2 inhibits sphingosine acyltransferase, disrupting sphingolipid metabolism.…
Furosemide Furosemide is a loop diuretic that is clinically used to treat congestive heart failure, edema, and hypertension; it inhibits the Na+/K+/Cl2- (NKCC) symporter and CFTR Cl- channels in the…
Gallic Acid Gallic acid is a phenol found in various plants including sumac, oak, and witch hazel; it exhibits neuroprotective, antioxidative, anticancer, anti-metastatic, antibiotic, antacid, and anti-ulcerative activities. Gallic acid…