Enterostatin, pig/rat
Enterostatin, pig/rat Enterostatin is an endogenous anorexigenic peptide that regulates dietary fat intake and inhibits insulin secretion. Enterostatin binds the F1-ATPase β subunit and decreases serum cholesterol in a CCK-1…
Ubiquitin Ligase- ubiquitin-ligase
Entinostat
Entinostat Entinostat is a benzamide derivative that inhibits histone deacetylase 1 (HDAC1); entinostat exhibits anticancer chemotherapeutic, anti-metastatic, and neuroprotective properties. In vitro, entinostat increases transcription of E-cadherin and decreases transcription…
Epigallocatechin Gallate
Epigallocatechin Gallate Epigallocatechin gallate (EGCG) is a flavonoid (flavanol) found in Camilla (green tea); it is one of several green tea catechins. EGCG exhibits neuroprotective, antioxidative, anti-inflammatory, anti-diabetic, antifungal, anti-metastatic,…
Epigallocatechin Gallate Octaacetate
Epigallocatechin Gallate Octaacetate Peracetylated epigallocatechin-3-gallate (AcEGCG) is a close relative of epigallocatechin-3-gallate, a catechin found in green tea (Camellia sinensis). AcEGCG has a higher bioavailability than its parent compound and…
Epimedin C
Epimedin C Epimedin C is a flavonoid originally found in Epimedium sagittatum; it exhibits immunostimulatory and anticancer activities. In hepatoma cells, epimedin C inhibited cellular proliferation by decreasing expression of…
Epirubicin Hydrochloride
Epirubicin Hydrochloride Epirubicin is an anthracycline that exhibits anticancer chemotherapeutic activity; it is an isomer of doxorubicin. Epirubicin acts as a DNA intercalator and topoisomerase II inhibitor, inhibiting DNA and…
Eplerenone
Eplerenone Eplerenone displays antihypertensive, anti-inflammatory, and anti-angiogenic activities; it inhibits the mineralocorticoid receptor. Eplerenone inhibits aldosterone-induced expression of COX (therefore decreasing PGE2 levels), preventing the induction of COX and resulting…
Epothilone A
Epothilone A Epothilone is an anticancer chemotherapeutic that acts as an anti-mitotic compound; it binds the taxane pocket of β-tubulin, using side chains to induce formation of a short helix…
Epothilone B
Epothilone B Epothilone is an anticancer chemotherapeutic and neuroprotective compound that acts as an antimitotic compound; it binds the taxane pocket of β-tubulin, using side chains to induce formation of…
Epothilone D
Epothilone D Epothilone is an anticancer chemotherapeutic that acts as an anti-mitotic compound; it binds the taxane pocket of β-tubulin, using side chains to induce formation of a short helix…