Dihydrochelerythrine Dihydrochelerythrine (DHC) is a benzophenanthridine alkaloid originally found in the stem bark of Garcinia. This compound exhibits a wide variety of antimicrobial activities (anti-parasitic, antifungal, and antibacterial) as well…
Dihydrocytochalasin B Dihydrocytochalasin B is a mycotoxin derivative that inhibits actin polymerization, preventing mitosis. Dihydrocytochalasin B exhibits anti-parasitic activity, inhibiting the growth of Entamoeba invadens. Additionally, dihydrocytochalasin B exhibits neuromodulatory…
Dihydrokainic Acid Dihydrokainic acid is an inhibitor of GLT-1, preventing cellular uptake of glutamate. Dihydrokainic acid exhibits neuromodulatory activity and may induce excitotoxicity and excessive NMDA receptor activation. In vivo,…
Dihydromethysticin Dihydromethysticin is a kavalactone originally found in Piper methysticum (kava plant) that exhibits antifungal, antiepileptic/anticonvulsant, neuroprotective, anticancer, and chemopreventive activities. This compound displays antimicrobial efficacy against species of Fusarium,…
Dihydromyristicin Dihydromyristicin was originally found in umbelliferous plants such as parsley; it exhibits antioxidative and chemopreventive activities. Dihydromyristicin induces phase II enzymes and inhibits benzopyrene-induced carcinogenesis in vivo. References PubMed…
Dihydrosanguinarine Dihydrosanguinarine (DHS) is a benzophenanthridine alkaloid that is a metabolite of sanguinarine. This compound exhibits a wide variety of antimicrobial activities (anti-parasitic, antifungal, and antibacterial) as well as anticancer…
Dihydrotanshinone Dihydrotanshinone is found in Salvia that exhibits neuromodulatory, anticancer, anti-inflammatory, anti-allergic, anti-diabetic, antithrombotic, vasodilatory, antihypertensive, and anti-angiogenic activities. Dihydrotanshinone binds to the P-site of acetylcholinesterase (AChE), inhibiting its activity…
Diltiazem Hydrochloride Diltiazem is a benzothiazepine-type compound that acts as an inhibitor of L-type Ca2+ channels. Diltiazem exhibits anti-arrhythmic, anti-anginal, anti-inflammatory, and cardioprotective activities. In animal models, diltiazem inhibits expression…
Dimebon Dihydrochloride Dimebon is an activator of AMPK, a potentiator of AMPA, and an inhibitor of L-type voltage-gated Ca2+ channels, NMDA receptors, H1/2 histamine receptors, α-adrenergic receptors, and 5-HT2C/5A/6 receptors.…
Dimethoxycurcumin Like its parent compound, curcumin, this curcuminoid exhibits anticancer, antioxidative, anti-inflammatory, and antibacterial activities. In breast cancer cells, dimethoxycurcumin alters mitochondrial membrane potential, decreases ATP synthase activity, and induces…