TL-32711
TL-32711 TL-32711 is a Smac mimetic that is currently in clinical trials as a potential treatment for a variety of cancers. TL-32711 inhibits members of the inhibitor of apoptosis protein…
2017
Tivozanib
Tivozanib Tivozanib is an anticancer chemotherapeutic and anti-angiogenic compound that inhibits VEGFR1/2/3, c-Kit, and PDGFR. Tivozanib is currently in clinical trials as a potential treatment for renal cell carcinoma. The…
Tivantinib
Tivantinib Tivantinib is an inhibitor of MET and GSK-3α/β that exhibits anticancer chemotherapeutic activity. Tivantinib inhibits proliferation of non-small cell lung cancer (NSCLC) cells and is currently undergoing clinical trials,…
Tirasemtiv
Tirasemtiv Tirasemtiv is an activator of the fast skeletal muscle troponin complex that sensitizes the sarcomere to Ca2+ and increases muscle force. Tirasemtiv displays neuromodulatory activity; it improves motor functions…
Tirapazamine
Tirapazamine Tirapazamine is an anticancer chemotherapeutic compound currently in clinical trials co-administered with cisplatin or radiation as a potential treatment for several cancers. Tirapazamine inhibits DNA topoisomerase IIα and modulates…
Tiplaxtinin
Tiplaxtinin Tiplaxtinin inhibits plasminogen activator inhibitor 1 (PAI-1), decreasing would closure and collagen deposition. Tiplaxtinin exhibits anti-inflammatory, anti-fibrotic, anti-allergic, anti-angiogenic, and anticancer chemotherapeutic activities. Tiplaxtinin inhibits carotid artery neointimal formation…
Tioconazole
Tioconazole Tioconazole is an imidazole antifungal and antibacterial compound that damages cell membranes. Tioconazole is most active against fungi, molds, and gram positive bacteria. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18976554/ Cas No. 65899-73-2…
Tibolone
Tibolone Tibolone is a synthetic steroid hormone selective estrogen receptor modulator (SERM) that acts as an agonist or antagonist depending on the tissue location. Tibolone exhibits anti-osteoporotic, vasodilatory, and anti-metastatic…
Thyrotropin-releasing Hormone, Free Acid
Thyrotropin-releasing Hormone, Free Acid Thyrotropin-releasing hormone (TRH) is an endogenous tripeptide that acts as a neurotransmitter and neurohormone. TRH regulates hypothalamic-pituitary-adrenal (HPA) and estrogenic signaling pathways. TRH exhibits immunomodulatory and…
Thyrotropin-releasing Hormone
Thyrotropin-releasing Hormone Thyrotropin-releasing hormone (TRH) is an endogenous tripeptide amide that acts as a neurotransmitter and neurohormone. TRH regulates hypothalamic-pituitary-adrenal (HPA) and estrogenic signaling pathways. TRH exhibits immunomodulatory and neuroprotective…