Topotecan Hydrochloride Topotecan is an anticancer chemotherapeutic compound that inhibits topoisomerase I and is clinically used to treat various cancers. Topotecan induces apoptosis in retinocytoma cells and ovarian cancer cells.…
Tolvaptan Tolvaptan is an inhibitor of the vasopressin receptor subtype V2; it acts as a diuretic, inhibiting reabsorption of water in the kidney without loss of sodium. Tolvaptan is a…
Toltrazuril Toltrazuril is an anti-parasitic compound that inhibits mitochondrial respiration and pyrimidine synthesis. Toltrazuril treats coccidiosis in livestock and is also active against Toxoplasma and other microbes. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18977120…
Tolmetin Sodium Tolmetin is a pyrrole non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory and analgesic activities. Tolmetin inhibits COX-1 and COX-2, preventing prostaglandin E (PGE) production; it is clinically used…
Tolfenamic Acid Tolfenamic acid is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and anticancer chemotherapeutic activities; it inhibits COX-1 and COX-2. Tolfenamic acid inhibits leukotriene B4 (LTB4) production,…
Tofacitinib Citrate Tofacitinib is an inhibitor of JAK1/2/3 that is clinically used to treat myelofibrosis and rheumatoid arthritis. Tofacitinib exhibits immunosuppressive, anti-inflammatory, and antiviral activities. In vitro, tofacitinib inhibits production…
Tobramycin, Free Base Tobramycin is an aminoglycoside antibiotic that exhibits antibacterial and anti-inflammatory activities. Tobramycin prevents formation of the 70S bacterial ribosomal complex, inhibiting protein translation; it is highly effective…
Tobramycin Sulfate Tobramycin is an aminoglycoside antibiotic that exhibits antibacterial and anti-inflammatory activities. Tobramycin prevents formation of the 70S bacterial ribosomal complex, inhibiting protein translation; it is highly effective in…
TMP-269 TMP-269 is an inhibitor of class II histone deacetylases (HDACs) that exhibits anticancer activity. In intestinal epithelial cells, TMP-269 inhibits cell cycle progression and cell proliferation. In multiple myeloma…
TM3-0089 Sodium Monohydrate TM3-0089 is an inhibitor of chemoattractant receptor-homologous molecule on Th2 cells (CRTH2), which inhibits prostaglandin activation of Th2 cells. TM3-0089 exhibits anti-allergic and anti-inflammatory activities. TM3-0089 prevents…