Valdecoxib
Valdecoxib Valdecoxib is a COX inhibitor specific for COX-2; it also inhibits carbonic anhydrase. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory and analgesic activities. In addition to…
2017
Usnic Acid
Usnic Acid Usnic acid is a dibenzofuran initially produced by lichens and exhibits antibacterial, anti-angiogenic, and anticancer chemotherapeutic activities. Usnic acid displays antibiotic activity against Mycobacterium tuberculosis. In lung carcinoma…
Uroguanylin, human
Uroguanylin, human Uroguanylin is an endogenous natriuretic peptide that modulates activity through Na+/H+ exchangers in intestinal and renal tissues, altering electrolyte and water transport. Uroguanylin activates guanylyl cyclase receptors to…
Urocortin, human
Urocortin, human Urocortin is an endogenous peptide ligand and member of the corticotropin-releasing factor (CRF) family; it binds and activates CRF type 1 and 2 receptors. Urocortin modulates stress responses…
Universal Tetanus Toxin Epitope P2 (830-844)
Universal Tetanus Toxin Epitope P2 (830-844) Tetanus toxin (TT) epitope P2 (830-843) is universally immunogenic. This peptide fragment is used as an antigen to bind MHC receptors on T cells,…
Ubenimex
Ubenimex Ubenimex, also known as bestatin, is a dipeptide inhibitor of aminopeptidases such as aminopeptidase N/CD13. Bestatin displays efficacy in the treatment of lung cancer. This compound exhibits anticancer chemotherapeutic,…
Tuftsin
Tuftsin Tuftsin is a tetrapeptide that binds the neuropilin-1 (Nrp1) receptor, modulating TGF-β, cGMP, and Ca2+ signaling. Tuftsin is derived from the Fc region of IgG. Tuftsin exhibits immunomodulatory activity,…
Tubeimoside I
Tubeimoside I Tubeimoside I is a triterpene saponin originally found in Bolbostemma that exhibits anti-inflammatory, antiviral, anticancer chemotherapeutic, and chemopreventive activities. Tubeimoside I inhibits LPS-stimulated production of TNF-α, IL-1β, and…
Troglitazone
Troglitazone Troglitazone is a thiazolidinedione PPARγ agonist that exhibits anti-diabetic, anticancer, anti-fibrotic, and anti-inflammatory activities. Troglitazone contains a vitamin E-like ring structure that forms hepatotoxic metabolites in vivo. Troglitazone induces…
Triticonazole
Triticonazole Triticonazole is a triazole pesticide/fungicide with broad antifungal activity. Like many azole fungicides, triticonazole likely inhibits 14-α demethylase, inhibiting ergosterol production and fungal cell wall synthesis. Additionally, triticonazole may…