Baccatin III
Baccatin III Baccatin III is a diterpene found in Taxus and various fungal organisms that exhibits immunomodulatory and anticancer chemotherapeutic activities. Unlike most taxanes, baccatin III does not bind tubulin;…
2017
B-type Natriuretic Peptide (1-32), rat
B-type Natriuretic Peptide (1-32), rat Brain natriuretic peptide (BNP) binds the natriuretic peptide receptor type B (NPR-B) to exert cardiomodulatory activity. BNP is secreted by the heart; it displays lipolytic…
B-type Natriuretic Peptide (1-32), human
B-type Natriuretic Peptide (1-32), human Brain natriuretic peptide (BNP) binds the natriuretic peptide receptor type B (NPR-B) to exert cardiomodulatory activity. BNP is secreted by the heart; it displays lipolytic…
B-Raf IN 1
B-Raf IN 1 B-Raf IN 1 inhibits both B-Raf and c-Raf, likely displaying anticancer activity. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18842813 Cas No. 950736-05-7 Purity ≥98% Formula C29H24F3N5O Formula Wt. 515.54 IUPAC Name…
Azelastine Hydrochloride
Azelastine Hydrochloride Azelastine is a second generation antihistamine that inhibits H1 histamine receptors. Azelastine exhibits anti-allergic, anti-inflammatory, and anti-tussive activities and is clinically used to treat allergic rhinitis. Azelastine activates…
AZD-8330
AZD-8330 AZD-8330 is an inhibitor of MEK1/2 that exhibits anticancer chemotherapeutic activity. AZD-8330 is currently in clinical trials for the treatment of advanced stage cancers. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18842808 Cas No.…
AZD-8055
AZD-8055 AZD-8055 is an ATP-competitive mTORC1/2 inhibitor that exhibits immunosuppressive and anticancer chemotherapeutic activities. AZD-8055 promotes antibody class switching in B cells at low doses and decreases B cell proliferation…
AZD-7762 Hydrochloride
AZD-7762 Hydrochloride AZD-7762 is an inhibitor of checkpoint kinase 1 (Chk1) that increases sensitivity to DNA-damaging compounds. AZD-7762 exhibits anticancer chemotherapeutic activity and is currently in clinical trials as a…
AZD-6482
AZD-6482 AZD-6482 is an inhibitor of p110β PI3K. AZD-6482 inhibits insulin-induced adipocyte glucose uptake in vitro and increases glucose homeostasis in vivo. Additionally, AZD-6482 exhibits antithrombotic activity without increasing bleeding…
Atriopeptin III
Atriopeptin III Atriopeptin III is an analog of atrial natriuretic peptide (ANP) that exhibits vasodilatory/hypotensive and diuretic activities. In rat kidneys, atriopeptin III increases the diameter of constricted afferent arterioles,…