Ebastine
Ebastine Ebastine is a second-generation antihistamine and anti-inflammatory compound that is clinically used to treat allergic rhinitis. Like other newer antihistamines, administration of ebastine results in less of a sedative…
2017
E64-d
E64-d E64d is an inhibitor of cathepsins that exhibits neuroprotective activity. In vivo, E64d inhibits cathepsin D, decreasing brain amyloid-β (Aβ) plaque formation. E64d inhibition of cathepsins also aggravates left…
E64
E64 E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1889806 Cas No. 66701-25-5 Purity ≥98% Formula C15H27N5O5 Formula Wt. 357.41 IUPAC Name…
E-JIB-04
E-JIB-04 This compound is the E stereoisomer of JIB-04, an inhibitor of Jumonji family histone demethylases; it does not inhibit activity of α-ketoglutarate. JIB-04 exhibits anticancer chemotherapeutic activity, inhibiting protein…
Dynasore
Dynasore Dynasore is an inhibitor of dynamin, a protein involved in membrane fission during endocytosis; it displays anti-resorptive, anti-osteoporotic, and antiviral activities. Dynasore inhibits bone resorption by preventing actin ring…
Droloxifene
Droloxifene Droloxifene is an anti-estrogen triphenylthylene selective estrogen receptor modulator (SERM); it is an analog of tamoxifen. Droloxifene acts as an estrogen receptor agonist in bone and as an estrogen…
Doxycycline Monohydrate
Doxycycline Monohydrate Doxycycline is a tetracycline antibiotic that exhibits anti-parasitic, anti-helminthic, anti-inflammatory, anticancer, and anti-metastatic activities. Doxycycline exerts its antibacterial activity through binding 16S rRNA of the bacterial 30S ribosome,…
Doxycycline Hyclate
Doxycycline Hyclate Doxycycline is a tetracycline antibiotic that exhibits anti-parasitic, anti-helminthic, anti-inflammatory, anticancer, and anti-metastatic activities. Doxycycline exerts its antibacterial activity through binding 16S rRNA of the bacterial 30S ribosome,…
Doxorubicin Hydrochloride
Doxorubicin Hydrochloride Doxorubicin is an anthracycline that exhibits anticancer chemotherapeutic and anti-parasitic, antimalarial activities. Doxorubicin is a DNA intercalator that inhibits topoisomerase II and is clinically used to treat various…
Doxofylline
Doxofylline Doxofylline is a xanthine derivative that inhibits phosphodiesterases (PDEs), but does not activate adenosine receptors. Doxofylline exhibits anti-asthma, anti-tussive, and bronchodilatory activities and is clinically used to treat asthma.…