Endomorphin-2 Endomorphin-2 is an endogenous agonist at μ-opioid receptors (μORs) in the spinal cord; it exhibits antinociceptive/analgesic, immunosuppressive, and pro-angiogenic activities. Endomorphin-2 increases pain thresholds in animal models of thermal…
Endomorphin-1 Endomorphin-1 is an endogenous agonist at μ-opioid receptors (μORs) in the spinal cord; it exhibits antinociceptive/analgesic, immunosuppressive, and pro-angiogenic activities. Endomorphin-1 increases pain thresholds in animal models of thermal…
Enalaprilat Dihydrate Enalaprilat is the active metabolite of enalapril. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that is clinically used to treat hypertension, heart failure, and diabetic nephropathy. Enalapril exhibits…
EMD 1214063 EMD 1214063 is an inhibitor of c-MET that exhibits anticancer chemotherapeutic activity. In animal models of hepatocellular carcinoma, EMD 1214063 inhibits tumor growth and induces complete regression. In…
Emamectin B1 Benzoate Emamectin B1 is a semi-synthetic avermectin that is clinically used in veterinary medicine; it exhibits anti-helminthic and anti-parasitic activities. Like other avermectins, emamectin increases GABA release, causing…
Elvitegravir Elvitegravir is an antiviral compound that inhibits integrase activity. This compound is clinically used to treat HIV infection. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1890122 Cas No. 697761-98-1 Purity ≥98% Formula C23H23ClFNO5 Formula…
ELR-510444 ELR-510444 inhibits microtubule polymerization through binding tubulin at the colchicine site; it exhibits anti-angiogenic and anticancer chemotherapeutic activities. ELR-510444 inhibits cell proliferation and tumor growth in models of breast…
Ellagic Acid Ellagic acid is a phenol found in various fruits that exhibits neuroprotective, anti-angiogenic, anti-inflammatory, anti-asthma, anti-allergic, antiviral, antioxidative, anti-parasitic, antimalarial, anticancer, and anti-ulcerative activities. Ellagic acid inhibits HIF-1α-induced…
Elcatonin Acetate Elcatonin is a synthetic analog of eel calcitonin that exhibits analgesic, anti-allodynic, antacid, and anti-resorptive activities. In animal models, elcatonin inhibits the effects of thermal and mechanical pain;…
Ebselen Ebselen is a synthetic glutathione peroxidase mimetic that reacts with cysteine residues; it exhibits antimicrobial, antibacterial, anti-diabetic, and antioxidative activities. Ebselen increases ROS and mitochondrial membrane potential, inhibiting GDH…