Kaempferol Kaempferol is a flavonol found in many plant sources that exhibits antioxidative, anti-inflammatory, neuroprotective, anti-angiogenic, anti-metastatic, anti-obesity, and anticancer chemotherapeutic activities. Kaempferol inhibits LPS-induced release of TNF-α, IL-1β, IL-6,…
K252c K252c is an aglycone analog of staurosporine that acts as a protein kinase inhibitor, inhibiting PKC and potentially PKA. K252c inhibits proliferation of human cytomegalovirus (CMV) and induces apoptosis…
K252b K252b is a cell membrane-impermeable analog of staurosporine that inhibits PKC. K252b inhibits production of hepatocyte growth factor and inhibits synthesis of DNA in vitro. K252b also inhibits various…
K252a K252a is an aglycone analog of staurosporine that acts as a protein kinase inhibitor, inhibiting PKC. K252a also inhibits TrkA/B receptors, suppressing activity of neurotrophins such as nerve growth…
JW55 JW55 is an inhibitor of tankyrases (TNKS1/2) that stabilizes the β-catenin degradation complex, suppressing Wnt signaling. JW55 displays anti-obesity and potential anticancer activities. In animal models of high-fat diet…
JNJ-26854165 JNJ-26854165 is an inhibitor of E3 ligase MDM2 that also indirectly activates p53. This compound exhibits anticancer chemotherapeutic activity, decreasing survival of various cancer cell lines and delaying tumor…
JC-1 JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18936064 Cas No. 3520-43-2 Purity ≥90% Formula C25H27Cl4IN4 Formula Wt.…
Jatrorrhizine Chloride Jatrorrhizine is an alkaloid compound originally found in Corydalis and Coptydis tubers that exhibits anticancer, neuroprotective, anti-parasitic, antioxidative, and gastrointestinal modulatory activities. Jatrorrhizine increases expression of p21 and…
Jatrorrhizine Jatrorrhizine is an alkaloid compound originally found in Corydalis and Coptydis tubers that exhibits anticancer, neuroprotective, anti-parasitic, antioxidative, and gastrointestinal modulatory activities. Jatrorrhizine increases expression of p21 and p27,…
Jasplakinolide Jasplakinolide is a marine toxin that stabilizes actin by inducing polymerization and preventing depolymerization and is used in research models. In animal models, jasplakinolide stimulates follicule growth. References PubMed…