Oligomycin
Oligomycin This product consists of a mixture of oligomycins A, B and C. Oligomycins are macrolide antibiotics that exhibit antibacterial activity. Oligomycins suppress oxidative phosphorylation in the mitochondria by inhibiting…
2017
Oleanolic Acid
Oleanolic Acid Oleanolic acid is a triterpenoid originally found in Vigna angularis and Trigonella foenum-graecum. Oleanolic acid exhibits anticancer, anti-inflammatory, anti-allergic, anti-resorptive, and anti-osteoporotic activities. In hypertrophic scar fibroblasts, oleanolic…
Olaparib
Olaparib Olaparib is an inhibitor of poly(ADP-ribose) polymerase (PARP 1/2) that prevents DNA repair. Olaparib displays benefit in clinical trials of BRCA mutation-harboring ovarian and breast cancers as well as…
Olanzapine
Olanzapine Olanzapine is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, panic disorder, anxiety, and Tourette’s syndrome. Olanzapine acts as an antagonist or inverse agonist at D1-4 receptors, 5-HT1A/2/3/6/7…
Okadaic Acid Sodium
Okadaic Acid Sodium Okadaic acid is a diarrhetic shellfish toxin initially produced by dinoflagellates and sea sponges; it exhibits neurotoxic and anticancer activities. Okadaic acid inhibits protein phosphatases 1 and…
Okadaic Acid Ammonium
Okadaic Acid Ammonium Okadaic acid is a diarrhetic shellfish toxin initially produced by dinoflagellates and sea sponges; it exhibits neurotoxic and anticancer activities. Okadaic acid inhibits protein phosphatases 1 and…
Okadaic Acid
Okadaic Acid Okadaic acid is a diarrhetic shellfish toxin initially produced by dinoflagellates and sea sponges; it exhibits neurotoxic and anticancer activities. Okadaic acid inhibits protein phosphatases 1 and 2A…
NSI-189
NSI-189 NSI-189 increases hippocampal volume and stimulates neurogenesis of hippocampal stem cells in vivo and in vitro. This compound may improve consolidation of information from short-term to long-term memory. In…
NS-11394
NS-11394 NS-11394 is a positive modulator of GABA-A receptor activity that is somewhat specific for α5/3/2 subunits. This compound exhibits analgesic and anxiolytic activities. In vivo, NS-11394 decreases formalin-induced pain…
NPS-2143 Hydrochloride
NPS-2143 Hydrochloride NPS-2143 is an antagonist at Ca2+-sensing receptors. It displays anti-osteoporotic, neuroprotective, cardioprotective, and antihypertensive activities. This calcilytic increases bone turnover without decreasing bone mineral density. NPS-2143 also inhibits…