Harringtonine Harringtonine is a cephalotaxine alkaloid originally found in Cephalotaxus hainanensis Li; it exhibits antiviral and anticancer activities. Harringtonine immobilizes initiated ribosomes, inhibiting protein translation by binding the A site…
Haloperidol Haloperidol is a butyrophenone antipsychotic that is clinically used to treat psychosis, obsessive-compulsive disorder, and various other personality disorders. Haloperidol acts as an antagonist at D2 receptors, α1-adrenergic receptors,…
H89 H89 is an inhibitor of PKA that is used to study the effects of PKA signaling in research models. H89 may also inhibit Rho-associated protein kinase (ROCK), S6K1, MSK1,…
H8 dihydrochloride H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18930064 Cas No. 113276-94-1 Purity ≥98% Formula C12H15N3O2S 2HC1 Formula Wt. 338.25 Chemical Name…
H7 H7 is an inhibitor of PKC and PKG that is used to study the effects of protein kinase signaling in research models. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18930016 Cas No. 108930-17-2 Purity…
H-Trp-Gly-OH Trp-Gly is a dipeptide used to study ultraviolet absorption and fluorescence of tryptophan-containing peptides. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18929978 Purity ≥98% Formula C13H13N3O2 Formula Wt. 261.28 Synonym Trp-Gly Ehlerding A, Wyer…
GW-788388 GW-788388 inhibits activin receptor-like kinase 5 (ALK5), suppressing TGF-β activity; it exhibits anti-fibrotic and cardioprotective activities. GW-788388 increases survival in studies of Trypanosoma infection and prevents Chagas disease-induced development…
GW-5074 GW-5074 is an indole that functions as a highly selective Raf-1 (c-Raf) kinase inhibitor and is used to study Ras/Raf-1/ERK signaling. This compound inhibits desuccinylation activity of Sirt5 (a…
Guggulsterone Guggulsterone is a plant steroid obtained from myrrh that exhibits a wide variety of beneficial properties, including anti-metastatic, anticancer, anti-angiogenic, anti-fibrotic, antioxidative, anti-inflammatory, and anti-hyperlipidemic activities. In vitro, guggulsterone…
Guanylin, rat/mouse Guanylin is a gastrointestinal peptide hormone that activates guanyl cyclase C primarily in intestinal epithelial cells, but also in neurons. Guanylin increases intracellular levels of cGMP and induces…