IOX2 IOX2 is an inhibitor of prolyl hydroxylase that activates HIF-1α and as a result, exhibits pro-angiogenic activity. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18931681 Cas No. 931398-72-0 Purity ≥98% Formula C19H16N2O5 Formula Wt.…
Ionomycin, Free Acid Ionomycin is a polyether antibiotic that acts as a Ca2+ ionophore, modulating intracellular Ca2+ signaling to increase cytosolic Ca2+ levels. Ionomycin modulates Ca2+ signaling across many cell…
Ionomycin Calcium Ionomycin is a polyether antibiotic that acts as a Ca2+ ionophore, modulating intracellular Ca2+ signaling to increase cytosolic Ca2+ levels. Ionomycin modulates Ca2+ signaling across many cell types…
Iohexol Iohexol is a low osmolarity contrast agent used to visualize vasculature in coronary imaging procedures. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18931626 Cas No. 66108-95-0 Purity ≥98% Formula C19H26I3N3O9 Formula Wt. 821.14 Chemical…
Interleukin-6 Receptor Fragment This peptide fragment of the soluble IL-6 receptor binds IL-6 weakly but does not display significant downstream signaling effects. This peptide may be used to measure presence…
Indirubin Indirubin is a bisindole isomer of indigo found in Indigo naturalis. Indirubin exhibits anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities. In vivo, indirubin decreases levels of IgE and production of…
Indapamide Indapamide is a thiazide-like diuretic that exhibits antihypertensive and anti-fibrotic activities. Indapamide is clinically used to treat hypertension and heart failure. Indapamide blocks the slow component of delayed rectifier…
INCB018424 INCB018424 is an inhibitor of JAK1/2 that is clinically used to treat rheumatoid arthritis and myelofibrosis. INCB018424 exhibits anticancer, anti-inflammatory, and antiviral activities. In myeloma cells, INCB018424 inhibits cell…
INCB-28060 INCB28060 is an inhibitor of c-MET that exhibits anticancer chemotherapeutic activity. In cellular models of cancer, INCB28060 inhibits cell migration and induces apoptosis, inhibiting proliferation. In animal models, this…
Inauhzin Inauhzin is an inhibitor of SIRT1 that activates p53; it also inhibits inosine monophosphate dehydrogenase (IMPDH). Inauhzin exhibits anticancer chemotherapeutic activities, inducing apoptosis and suppressing cell growth in non-small…