Torin 2
Torin 2 Torin 2 1 is a tricyclic benzonaphthyridinone that inhibits mTORC1/2 and exhibits anticancer activity. In hepatocellular carcinoma cells, torin 2 inhibits cell growth and survival and induces apoptosis…
June 2017
Torin 1
Torin 1 Torin 1 is a tricyclic benzonaphthyridinone that inhibits mTORC1/2 and exhibits anti-inflammatory, anti-angiogenic, anti-metastatic, and anticancer chemotherapeutic activities. In macrophages, torin 1 decreases cytokine production and inflammatory response…
Toremifene Base
Toremifene Base Toremifene is a selective estrogen receptor modulator (SERM) that also moderates androgen receptor activity as well. Toremifene displays anticancer chemotherapeutic and anti-angiogenic activities. Clinically, this compound is used…
Torcetrapib
Torcetrapib Torcetrapib is a cholesterol ester transfer protein (CETP) inhibitor that exhibits anti-atherosclerotic and anti-diabetic activities. In vivo, this compound increases levels of HDL and glucose uptake and decreases levels…
Topotecan Hydrochloride
Topotecan Hydrochloride Topotecan is an anticancer chemotherapeutic compound that inhibits topoisomerase I and is clinically used to treat various cancers. Topotecan induces apoptosis in retinocytoma cells and ovarian cancer cells.…
Tolvaptan
Tolvaptan Tolvaptan is an inhibitor of the vasopressin receptor subtype V2; it acts as a diuretic, inhibiting reabsorption of water in the kidney without loss of sodium. Tolvaptan is a…
Toltrazuril
Toltrazuril Toltrazuril is an anti-parasitic compound that inhibits mitochondrial respiration and pyrimidine synthesis. Toltrazuril treats coccidiosis in livestock and is also active against Toxoplasma and other microbes. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18977120…
Tolmetin Sodium
Tolmetin Sodium Tolmetin is a pyrrole non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory and analgesic activities. Tolmetin inhibits COX-1 and COX-2, preventing prostaglandin E (PGE) production; it is clinically used…
Tolfenamic Acid
Tolfenamic Acid Tolfenamic acid is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and anticancer chemotherapeutic activities; it inhibits COX-1 and COX-2. Tolfenamic acid inhibits leukotriene B4 (LTB4) production,…
Tofacitinib Citrate
Tofacitinib Citrate Tofacitinib is an inhibitor of JAK1/2/3 that is clinically used to treat myelofibrosis and rheumatoid arthritis. Tofacitinib exhibits immunosuppressive, anti-inflammatory, and antiviral activities. In vitro, tofacitinib inhibits production…