Tobramycin, Free Base Tobramycin is an aminoglycoside antibiotic that exhibits antibacterial and anti-inflammatory activities. Tobramycin prevents formation of the 70S bacterial ribosomal complex, inhibiting protein translation; it is highly effective…
Tobramycin Sulfate Tobramycin is an aminoglycoside antibiotic that exhibits antibacterial and anti-inflammatory activities. Tobramycin prevents formation of the 70S bacterial ribosomal complex, inhibiting protein translation; it is highly effective in…
TMP-269 TMP-269 is an inhibitor of class II histone deacetylases (HDACs) that exhibits anticancer activity. In intestinal epithelial cells, TMP-269 inhibits cell cycle progression and cell proliferation. In multiple myeloma…
TM3-0089 Sodium Monohydrate TM3-0089 is an inhibitor of chemoattractant receptor-homologous molecule on Th2 cells (CRTH2), which inhibits prostaglandin activation of Th2 cells. TM3-0089 exhibits anti-allergic and anti-inflammatory activities. TM3-0089 prevents…
TL-32711 TL-32711 is a Smac mimetic that is currently in clinical trials as a potential treatment for a variety of cancers. TL-32711 inhibits members of the inhibitor of apoptosis protein…
Tivozanib Tivozanib is an anticancer chemotherapeutic and anti-angiogenic compound that inhibits VEGFR1/2/3, c-Kit, and PDGFR. Tivozanib is currently in clinical trials as a potential treatment for renal cell carcinoma. The…
Tivantinib Tivantinib is an inhibitor of MET and GSK-3α/β that exhibits anticancer chemotherapeutic activity. Tivantinib inhibits proliferation of non-small cell lung cancer (NSCLC) cells and is currently undergoing clinical trials,…
Tirasemtiv Tirasemtiv is an activator of the fast skeletal muscle troponin complex that sensitizes the sarcomere to Ca2+ and increases muscle force. Tirasemtiv displays neuromodulatory activity; it improves motor functions…
Tirapazamine Tirapazamine is an anticancer chemotherapeutic compound currently in clinical trials co-administered with cisplatin or radiation as a potential treatment for several cancers. Tirapazamine inhibits DNA topoisomerase IIα and modulates…
Tiplaxtinin Tiplaxtinin inhibits plasminogen activator inhibitor 1 (PAI-1), decreasing would closure and collagen deposition. Tiplaxtinin exhibits anti-inflammatory, anti-fibrotic, anti-allergic, anti-angiogenic, and anticancer chemotherapeutic activities. Tiplaxtinin inhibits carotid artery neointimal formation…