JC-1 JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18936064 Cas No. 3520-43-2 Purity ≥90% Formula C25H27Cl4IN4 Formula Wt.…
Jatrorrhizine Chloride Jatrorrhizine is an alkaloid compound originally found in Corydalis and Coptydis tubers that exhibits anticancer, neuroprotective, anti-parasitic, antioxidative, and gastrointestinal modulatory activities. Jatrorrhizine increases expression of p21 and…
Jatrorrhizine Jatrorrhizine is an alkaloid compound originally found in Corydalis and Coptydis tubers that exhibits anticancer, neuroprotective, anti-parasitic, antioxidative, and gastrointestinal modulatory activities. Jatrorrhizine increases expression of p21 and p27,…
Jasplakinolide Jasplakinolide is a marine toxin that stabilizes actin by inducing polymerization and preventing depolymerization and is used in research models. In animal models, jasplakinolide stimulates follicule growth. References PubMed…
JAK2 Inhibitor V JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation. References…
J-147 J-147 is a phenyl hydrazide that exhibits neuroprotective and cognition enhancing activities. In vitro, this compound decreases neuronal loss, oxidative stress, and glutamate-induced neurotoxicity. J-147 also ameliorates memory impairment…
IWP-2 IWP-2 is an inhibitor of PORCN that inhibits Wnt signaling, exhibiting anticancer activity. IWP-2 increases activity of caspases 3 and 7, inhibiting proliferation, migration, and invasion of gastric cancer…
Ivermectin Ivermectin is an avermectin-family antibiotic that exhibits anti-parasitic/anti-helminthic activity. Ivermectin activates glutamate-gated Cl- channels, interfering with neurotransmission and muscle function in arthropods and nematodes. At high doses, ivermectin also…
Itraconazole Itraconazole is a triazole antifungal that also exhibits anti-angiogenic and anticancer chemotherapeutic activities. Itraconazole inhibits synthesis of ergosterol, preventing fungal cell wall formation in Aspergillus. Itraconazole also inhibits hedgehog…
Itopride Hydrochloride Itopride is an inhibitor of acetylcholinesterase (AChE) and D2 receptors; it exhibits prokinetic gastrointestinal motility modulating activity. Itopride is clinically used to treat functional dyspepsia and gastroesophageal reflux…