MLN-2238 MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18945487 Cas No. 1072833-77-2…
MK-2461 MK-2461 is an inhibitor of MET that also shows inhibition of FGFR and PDGFR. In animal models of glioblastoma and gastric cancer, MK-2461 exhibits anticancer chemotherapeutic activity, decreasing tumor…
MK-2206 MK-2206 is an allosteric inhibitor of Akt that prevents translocation of Akt to membranes. MK-2206 exhibits anticancer chemotherapeutic activity in a variety of in vitro cancer models; this compound…
MK-0524 MK-0524 is a specific prostaglandin D2 receptor (DP1) inhibitor that functions as an inverse agonist. MK-0524 decreases niacin-induced flushing during niacin treatment of dyslipidemia and is most often studied…
Mizoribine Hydrobromide Mizoribine is an inhibitor of inosine monophosphate dehydrogenase (IMPDH) that exhibits immunosuppressive and, potentially, antifungal activities. Mizoribine is used clinically in organ transplantations and to treat rheumatoid arthritis…
Mivacurium Chloride Mivacurium is a non-depolarizing, reversible neuromuscular junction blocker. Mivacurium acts as an anesthetic, inhibiting pre-synaptic nicotinic acetylcholine receptors (nAChRs) in neurons and muscle. Mivacurium exhibits a rapid onset…
Mitoxantrone Dihydrochloride Mitoxantrone is an anthracenedione that exhibits immunosuppressive and anticancer chemotherapeutic activities. Mitoxantrone is clinically used to treat multiple sclerosis (MS), breast cancer, non-Hodgkin’s lymphoma, acute myeloid leukemia (AML),…
Mitotane Mitotane is an anticancer chemotherapeutic compound clinically used to treat adrenocortical carcinoma, as it targets only adrenal cells and not others. In adrenocortical cells, mitotane inhibits secretion of cortisol…
MitoPTTM JC-1 Assay kit This kit measures the initiation of cellular apoptosis. MitoPT is a trade mark of Immunochemistry Technology , LLC References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18945174 Synonym MitoPTTM 944396-07-1
Mifepristone Mifepristone is a synthetic steroid that exhibits abortifacient, contraceptive, neuroprotective, cognition enhancing, and antidepressant activities. Mifepristone inhibits the glucocorticoid receptor and progesterone receptor; it prevents ovulation and induces endometrial…