Palmitoyl-D,L-carnitine Palmitoyl-D,L-carnitine is a long chain acylcarnitine that is involved in fatty acid metabolism; it may be used as a substrate in the simulation of mitochondrial respiration. Palmitoyl-D,L-carnitine inhibits PKC…
Palmatine Chloride Hydrate Palmatine is an isoquinoline alkaloid found in Corydalis, Phellodendron, Enantia, and other plants. Palmatine exhibits sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities. Palmatine binds hemoglobin…
Paliperidone Paliperidone is an antipsychotic compound that inhibits D2 receptors and 5-HT2A receptors and is used to treat schizophrenia. Paliperidone also attenuates epinephrine- and serotonin-induced platelet aggregation. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18952469…
Palbociclib Isethionate Palbociclib is an inhibitor of CDK4 and CDK6 that displays anticancer chemotherapeutic and nephroprotective activities; it is currently in clinical trials as a potential treatment for breast cancer.…
Palbociclib Hydrochloride Palbociclib is an orally bioavailable selective inhibitor of CDK4 and CDK6, kinases that regulate cell cycle progression. This compound exhibits anticancer chemotherapeutic activity in a variety of models,…
Paeonol Paeonol was originally found in species of Paeonia, Arisaema, and Dioscorea. Paeonol exhibits anti-inflammatory, analgesic, neuromodulatory, vasodilatory, anticancer, anti-atherosclerotic, and anti-angiogenic activities. Paeonol inhibits carrageenan-induced thermal hyperalgesia and decreases…
Paeoniflorin Paeoniflorin is found in Paeonia; it exhibits anti-inflammatory, antioxidative, neuromodulatory, antidepressant, analgesic, and anticancer chemotherapeutic activities. In animal models of DSS-induced colitis, paeoniflorin decreases expression of toll-like receptor 4…
Paclitaxel, from Taxus yunnanensis Paclitaxel is a diterpene compound found in Taxus yunnanensis that exhibits anticancer chemotherapeutic and anti-angiogenic activities. Paclitaxel induces tubulin polymerization, forming stable but nonfunctional microtubules; it…
P7C3A20 P7C3A20 is a fluorinated aminopropyl carbazole; it is a more active analog of P7C3 that also exhibits antidepressant, cognition enhancing, and neuroprotective activities. In animal models of traumatic brain…
P7C3 P7C3 is an aminopropyl carbazole that displays neuroprotective, antidepressant, and cognition enhancing activities, particularly in models of Parkinson’s disease and amyotrophic lateral sclerosis (ALS). P7C3 promotes neurogenesis in vivo…