Parathyroid Hormone-Related Protein (1-34), human/rat PTH (parathyroid hormone)-related protein (PTH-RP) binds the PTH1 receptor and exhibits anti-osteoporotic, anti-angiogenic, and pro-fibrotic activities. PTH (1-34) is an endogenous peptide that is clinically…
Pantoprazole Pantoprazole is an H+/K+ ATPase inhibitor that exhibits antacid, anti-parasitic, and anticancer chemotherapeutic activities. Pantoprazole is clinically used to treat gastroesophageal reflux disease (GERD), although its inhibition of ROCK-2…
Pancuronium Bromide Pancuronium is a reversible, competitive inhibitor of post-synaptic nicotinic acetylcholine receptors (nAChRs) that acts as a non-depolarizing neuromuscular junction (NMJ) blocker. When used clinically, pancuronium induces skeletal muscle…
Pancreatic Polypeptide, human Pancreatic polypeptide is an endogenous neuropeptide Y-family hormone that exhibits anorexigenic activity. Pancreatic polypeptide binds the Y4 receptor to decrease food intake, increase locomotor activity, and stimulate…
Pancreatic Polypeptide, chicken Pancreatic polypeptide is an endogenous neuropeptide Y-family hormone that exhibits anorexigenic activity. Pancreatic polypeptide binds the Y4 receptor to decrease food intake, increase locomotor activity, and stimulate…
Pancreastatin, pig Pancreastatin is an endogenous peptide derived from chromogranin-A that regulates insulin action, inhibiting insulin secretion and increasing glucagon secretion. Pancreastatin binds and inhibits GRP78, decreasing insulin-stimulated glucose uptake…
Panaxatriol Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities. Panaxatriol increases expression of heme oxygenase 1 (HO-1) and…
Panaxadiol Panaxadiol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. Panaxadiol inhibits Ca2+ channels, decreasing channel open time and…
Pamidronate Disodium Pentahydrate Pamidronate is a bisphosphonate that exhibits anti-resorptive and anti-osteoporotic activities. Pamidronate is clinically used to prevent injury- or chemotherapy-induced bone loss. Clinically, pamidronate increases muscle fiber, bone…
Palmitoyl-L-carnitine Palmitoyl-L-carnitine is a long chain acylcarnitine that is involved in fatty acid metabolism. This compound is a substrate used to stimulate mitochondrial respiration and to study mitochondrial function in…